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Effects of Vitamin D3 Supplementation and Resistance Training on 25-Hydroxyvitamin D Status and Functional Performance of Older Adults: A Randomized Placebo-Controlled Trial.

Nutrients
January 1, 1970
Rudolf Aschauer et al. (8 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to examine the additive effects of vitamin D3 supplementation, alongside a fixed dose of calcium, during resistance training in older adults.

Results Summary

The study found that 25-hydroxyvitamin D (25(OH)D) status significantly improved in groups receiving vitamin D3 supplementation (daily or monthly) alongside calcium, but not in the control group. However, the abstract does not specify direct outcomes related to calcium's effects on muscle strength or performance.

Population

Seniors aged 65-85 years.

Effective Dosage

400 mg of calcium daily.

Duration

16 weeks (4-week loading phase followed by 10-week resistance training).

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
vitamin D3 supplementation
increase
25-hydroxyvitamin D (25(OH)D) status
100 seniors (65-85 years)
-
significantly improved
#1
resistance training
neutral
muscle strength endurance (30-s chair stand and arm curl tests)
100 seniors (65-85 years)
-
-
#2
resistance training
neutral
aerobic capacity (6-min walk test)
100 seniors (65-85 years)
-
-
#3
resistance training
neutral
functional mobility (gait speed and timed up and go test)
100 seniors (65-85 years)
-
-
#4
Abstract

Vitamin D status is associated with muscle strength and performance in older adults. To examine the additive effects of vitamin D3 supplementation during resistance training, 100 seniors (65-85 years) participated in a 16-week intervention. Besides a daily dose of 400 mg of calcium, participants received either 800 IU vitamin D3 per day (VDD), 50,000 IU vitamin D3 per month (VDM) or nothing (CON). After the initial loading phase of four weeks, all groups started a 10-week resistance training program. Assessments of 25-hydroxyvitamin D (25(OH)D) status, muscle strength endurance (30-s chair stand and arm curl tests), aerobic capacity (6-min walk test) and functional mobility (gait speed and timed up and go test) were undertaken at baseline, after four weeks and at the end of the study. 25(OH)D status significantly improved in VDD and VDM, but not in CON (time x group:

Medical Subject Headings (MeSH)
AgedAged, 80 and overCalcifediolCholecalciferolDietary SupplementsDouble-Blind MethodFemaleHumansMaleMuscle StrengthResistance TrainingVitamin D DeficiencyVitamins
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations15
Citations/Year3.8
Relative Citation Ratio1.66
NIH Percentile68.7%
Research Impact Scores
APT Score0.75
Weight Score1.77
Normalized Score0.67
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