Effects of Compound Danshen Injection Combined with Magnesium Sulfate on Pregnancy-Induced Hypertension Syndrome under the Guidance of Empirical Mode Decomposition Algorithm-Based Ultrasound Image.
Study Goal
The researchers aimed to evaluate the clinical efficacy of Compound Danshen injection combined with magnesium sulfate in treating pregnancy-induced hypertension (PIH) syndrome and improving maternal and infant outcomes.
Results Summary
The study found that Compound Danshen injection combined with magnesium sulfate significantly improved blood pressure control, reduced adverse maternal and infant outcomes, and lowered levels of ET-1, CRP, Hcy, and improved coagulation function compared to magnesium sulfate alone.
Population
80 patients with pregnancy-induced hypertension (PIH) syndrome.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
optimized empirical mode decomposition (EMD) algorithm | increase | accuracy and stability in separation of blood flow signals | - | - | were better than those of other algorithms | #1 |
Compound Danshen injection + magnesium sulfate | increase | total effective rate and blood pressure control | patients with PIH syndrome | - | were significantly better than those of the control group | #2 |
Compound Danshen injection + magnesium sulfate | decrease | incidence of adverse maternal and infant outcomes | patients with PIH syndrome | - | was significantly lower than that of the control group | #3 |
Compound Danshen injection + magnesium sulfate | decrease | endothelin-1 (ET-1), C-reactive protein (CRP), and homocysteine (Hcy) indexes | patients with PIH syndrome | - | decreased significantly | #4 |
Compound Danshen injection + magnesium sulfate | decrease | endothelin-1 (ET-1), C-reactive protein (CRP), and homocysteine (Hcy) indexes | patients with PIH syndrome | - | decrease level was significantly greater than that of the control group | #5 |
Compound Danshen injection + magnesium sulfate | increase | prothrombin time (PT), fibrinogen (FIB), activated partial thromboplastin time (APTT), and plasma thrombin time (TT) levels | patients with PIH syndrome | - | were better than those before treatment | #6 |
Compound Danshen injection + magnesium sulfate | increase | prothrombin time (PT), fibrinogen (FIB), activated partial thromboplastin time (APTT), and plasma thrombin time (TT) levels | patients with PIH syndrome | - | was better than the control group | #7 |
Compound Danshen injection combined with magnesium sulfate | increase | maternal and infant outcomes | patients with PIH syndrome | - | can improve | #8 |
Compound Danshen injection combined with magnesium sulfate | decrease | blood pressure | patients with PIH syndrome | - | control | #9 |
Compound Danshen injection combined with magnesium sulfate | decrease | 24 h urine protein and serum ET-1, Hcy, and CRP levels | patients with PIH syndrome | - | reduce | #10 |
Compound Danshen injection combined with magnesium sulfate | increase | coagulation function | patients with PIH syndrome | - | improve | #11 |
OBJECTIVE: The study focused on the separation effects of ultrasound blood flow signal detection, based on empirical mode decomposition (EMD) algorithm, and the clinical efficacy of Compound Danshen injection and magnesium sulfate in the treatment of pregnancy-induced hypertension (PIH) syndrome. METHODS: The empirical mode decomposition (EMD) algorithm was optimized first and compared with other algorithms for the accuracy and stability in separation of blood flow signals. 80 patients with PIH syndrome undergoing ultrasound examination were selected as the research subjects and randomly divided into control group and observation group according to the actual treatment methods. 40 cases in the observation group were treated with Compound Danshen injection + magnesium sulfate, and 40 cases in the control group were treated with magnesium sulfate. After the treatment, the clinical indicators of the two groups of patients were analyzed. RESULTS: The accuracy and stability in separating blood flow signal of the optimized EMD algorithm were better than those of other algorithms. After treatment, the total effective rate and blood pressure control of the observation group were significantly better than those of the control group, and the incidence of adverse maternal and infant outcomes was significantly lower than that of the control group. After treatment, the endothelin-1 (ET-1), C-reactive protein (CRP), and homocysteine (Hcy) indexes of the two groups of patients decreased significantly, and the decrease level of the observation group was significantly greater than that of the control group (P < 0.05). The prothrombin time (PT), fibrinogen (FIB), activated partial thromboplastin time (APTT), and plasma thrombin time (TT) levels of the two groups after treatment were better than those before treatment, and the observation group was better than the control group (P < 0.05). CONCLUSION: The optimized EMD algorithm is of great value for the separation of ultrasound blood flow signals. For patients with PIH syndrome, Compound Danshen injection combined with magnesium sulfate can be used as a treatment plan, which can improve maternal and infant outcomes; control blood pressure; reduce 24 h urine protein and serum ET-1, Hcy, and CRP levels; and improve coagulation function. It is worthy of promotion.