Iron Deficiency in Celiac Disease: Prevalence, Health Impact, and Clinical Management.
Study Goal
The researchers were examining the role of iron deficiency and related nutritional deficiencies in celiac disease patients.
Results Summary
The abstract highlights that iron deficiency anemia is common in celiac disease patients, potentially affecting over half at diagnosis, and mentions other contributing factors like folate and vitamin B12 malabsorption.
Population
Patients with celiac disease.
Effective Dosage
Not available
Duration
Not available
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
- | neutral | life | - | - | is an essential nutrient to | #1 |
- | neutral | erythropoiesis, oxidative, metabolism, and enzymatic activities | - | - | is required for | #2 |
- | neutral | mitochondrial respiratory chain enzymes, the citric acid cycle, and DNA synthesis | - | - | is a cofactor for | #3 |
- | increase | immune system cells | - | - | promotes the growth of | #4 |
Iron deficiency (ID) | decrease | the overall health of individuals | individuals | - | leads to deleterious effects on | #5 |
Iron deficiency (ID) | increase | significant morbidity | - | - | causing | #6 |
Iron deficiency anemia (IDA) | neutral | anemia | patients with celiac disease (CD) | - | is the most recognized type of | #7 |
Iron deficiency anemia (IDA) | neutral | patients | patients at the time of diagnosis | over half | may be present in over half of | #8 |
Iron is an essential nutrient to life and is required for erythropoiesis, oxidative, metabolism, and enzymatic activities. It is a cofactor for mitochondrial respiratory chain enzymes, the citric acid cycle, and DNA synthesis, and it promotes the growth of immune system cells. Thus, iron deficiency (ID) leads to deleterious effects on the overall health of individuals, causing significant morbidity. Iron deficiency anemia (IDA) is the most recognized type of anemia in patients with celiac disease (CD) and may be present in over half of patients at the time of diagnosis. Folate and vitamin B12 malabsorption, nutritional deficiencies, inflammation, blood loss, development of refractory CD, and concomitant