The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet is associated with physical function and grip strength in older men and women.
Study Goal
The researchers aimed to investigate associations between the MIND diet (a hybrid of Mediterranean and DASH diets) and physical function, grip strength, and functional impairment in older adults.
Results Summary
Higher adherence to the MIND diet was associated with lower odds of physical function impairment, slower functional decline, and greater grip strength in older adults over a median 6-year follow-up.
Population
Men and women (mean age 68 ± 14 years) from the Baltimore Longitudinal Study of Aging (n = 1358).
Effective Dosage
Not specified (diet assessed by FFQ, scored based on 15 food groups).
Duration
Median 6-year follow-up.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
MIND diet | decrease | physical function impairment | men and women in the Baltimore Longitudinal Study of Aging | OR: 0.81 per 1-point increment | inversely associated with | #1 |
MIND diet | decrease | each SPPB component | men and women in the Baltimore Longitudinal Study of Aging | - | inversely associated with | #2 |
MIND diet | decrease | functional impairment | Participants in the highest compared with the lowest tertile of MIND diet score | 57% | had lower odds of | #3 |
MIND diet | decrease | HABCPPB | Participants in the highest compared with the lowest tertile of MIND diet score | - | slower decline by | #4 |
MIND diet | increase | grip strength | Men in the highest compared with the lowest tertiles of MIND score | 1.86-kg | had greater | #5 |
MIND diet | increase | grip strength | Women in the highest compared with the lowest tertiles of MIND score | 1.24-kg | had greater | #6 |
MIND dietary pattern | decrease | physical function impairment and decline | older adults | - | associated with lower odds of | #7 |
MIND dietary pattern | increase | better muscle strength | older adults | - | associated with | #8 |
BACKGROUND: Diet quality may be protective of physical function and muscle strength during aging. OBJECTIVES: We aimed to investigate associations of the Mediterranean-Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet with physical function and grip strength. METHODS: Data were obtained from men and women in the Baltimore Longitudinal Study of Aging (mean ± SD age: 68 ± 14 y at first diet visit; n = 1358). Diet was assessed by FFQ. MIND diet score was calculated from 15 food groups, with a higher score indicating better diet quality; tertile categories of averaged MIND score across visits were used. Physical function was assessed using the Short Physical Performance Battery (SPPB), with a score < 10 indicative of impaired function, and the Health, Aging and Body Composition Physical Performance Battery (HABCPPB). The highest value of grip strength over 3 trials was used. Multivariable logistic and linear mixed-effects models were examined with repeated measurements of physical function and grip strength, respectively. RESULTS: MIND score was inversely associated with physical function impairment (per 1-point increment: OR: 0.81; 95% CI: 0.71, 0.93; P < 0.01), and with each SPPB component, over a median 6 y of follow-up. Participants in the highest compared with the lowest tertile of MIND diet score had 57% lower odds of functional impairment (OR: 0.43; 95% CI: 0.25, 0.73; P < 0.01), and slower decline by the HABCPPB. Men and women in the highest compared with the lowest tertiles of MIND score had 1.86-kg (95% CI: 0.33, 3.40 kg; P < 0.05) and 1.24-kg (95% CI: 0.04, 2.45 kg; P < 0.05) greater grip strength, respectively. CONCLUSIONS: Adherence to the MIND dietary pattern was associated with lower odds of physical function impairment and decline, and with better muscle strength, indicating that the MIND dietary pattern may be protective of physical functional health in older adults.