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Melatonin: a Potential Shield against Electromagnetic Waves.

Current neuropharmacology
January 1, 1970
Maya Jammoul et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to review the relationship between melatonin, electromagnetic fields (EMF), and oxidative stress, and to propose a model for melatonin's protective mechanisms against EMF-induced oxidative stress.

Results Summary

The study found that melatonin acts as a free radical scavenger, reducing oxidative stress caused by EMF exposure, and suggests potential therapeutic benefits against electromagnetic hypersensitivity (EHS).

Population

Not specified (general review of existing studies).

Effective Dosage

Not specified.

Duration

Not specified.

Interactions

None mentioned.

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
melatonin
neutral
various physiological functions and circadian rhythm regulation
-
-
has been implicated in
#1
melatonin
neutral
the non-ionizing electromagnetic field (EMF)
-
-
has a role in the protection against
#2
non-ionizing electromagnetic field (EMF)
decrease
the body's oxidative/anti-oxidative balance
-
-
disrupt
#3
melatonin
decrease
RF/ELF-EMF-induced oxidative stress
-
-
has protective effects against
#4
melatonin
decrease
the radical pair singlet-triplet conversion rate
-
-
can be enabled by reducing
#5
melatonin
decrease
the concentration of the triplet products
-
-
can be enabled by reducing
#6
melatonin
decrease
the detrimental effects of EMF
-
-
has potential therapeutic benefits against
#7
melatonin
decrease
electromagnetic hypersensitivity (EHS)
-
-
has potential therapeutic benefits against
#8
Abstract

Melatonin, a vital hormone synthesized by the pineal gland, has been implicated in various physiological functions and circadian rhythm regulation. Its role in the protection against the non-ionizing electromagnetic field (EMF), known to disrupt the body's oxidative/anti-oxidative balance, has been called into question due to inconsistent results observed across studies. This review provides the current knowledge on the interwoven relationship between melatonin, EMF, and oxidative stress. Based on synthesized evidence, we present a model that best describes the mechanisms underlying the protective effects of melatonin against RF/ELF-EMF-induced oxidative stress. It has been observed that the free radical scavenger activity of melatonin can be enabled by reducing the radical pair singlet-triplet conversion rate and the concentration of the triplet products. Moreover, this review aims to highlight the potential therapeutic benefits of melatonin against the detrimental effects of EMF, in general, and electromagnetic hypersensitivity (EHS), in particular.

Medical Subject Headings (MeSH)
Circadian RhythmElectromagnetic FieldsElectromagnetic RadiationHumansMelatoninOxidative StressPineal Gland
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations4
Citations/Year1.3
Relative Citation Ratio0.82
NIH Percentile43.1%
Research Impact Scores
APT Score0.25
Weight Score1.55
Normalized Score0.66
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