High-intensity interval training versus progressive high-intensity circuit resistance training on endothelial function and cardiorespiratory fitness in heart failure: A preliminary randomized controlled trial.
Study Goal
The researchers aimed to preliminarily assess the effects of high-intensity interval training (HIIT) and progressive high circuit-resistance training (CRT) on endothelial function, cardiorespiratory fitness, muscle strength, and physical performance in heart failure patients.
Results Summary
HIIT improved cardiorespiratory fitness (VO2 peak and METs) and isokinetic torque peak, while CRT improved physical performance (reduced chair stand test time). No significant effects were observed on endothelial function.
Population
Heart failure patients (aged 56 ± 10 years, mainly NYHA class I and II, hemodynamically stable).
Effective Dosage
At least 36 exercise sessions (specific frequency not detailed).
Duration
Duration not explicitly stated, but implied by the number of sessions.
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
high-intensity exercise training modalities, aerobic interval training (HIIT) | increase | VO2 peak | heart failure patients | +2.1±6.5 mL/kg/min | were able to produce a positive effect on | #1 |
progressive high circuit-resistance training (CRT) | increase | VO2 peak | heart failure patients | +3.0±4.2 mL/kg/min | were able to produce a positive effect on | #2 |
high-intensity exercise training modalities, aerobic interval training (HIIT) | increase | METs | heart failure patients | +0.6±1.8 | were able to produce a positive effect on | #3 |
progressive high circuit-resistance training (CRT) | increase | METs | heart failure patients | +0.9±1.2 | were able to produce a positive effect on | #4 |
high-intensity exercise training modalities, aerobic interval training (HIIT) | increase | isokinetic torque peak | heart failure patients | +8.8±55.8 Nm | increased | #5 |
progressive high circuit-resistance training (CRT) | decrease | chair stand test completion time | heart failure patients | -3.3±3.2 s | reduced | #6 |
high-intensity exercise training modalities, aerobic interval training (HIIT) | increase | global physical performance | heart failure patients | - | improved | #7 |
high-intensity exercise training modalities, aerobic interval training (HIIT) and progressive high circuit-resistance training (CRT) | no change | endothelial function | heart failure patients | - | no effects on | #8 |
INTRODUCTION: Exercise training is strongly recommended as a therapeutic approach to treat individuals with heart failure. High-intensity exercise training modalities still controversial in this population. The study aims to preliminary assess the consequences of high-intensity exercise training modalities, aerobic interval training (HIIT) and progressive high circuit-resistance training (CRT), on primarily endothelial function and cardiorespiratory fitness, and secondly on muscle strength and physical performance in heart failure patients. METHODS: This preliminary multicentric randomized controlled trial comprised 23 heart failure patients, aged 56 ± 10 years old, mainly New York Heart Association classification I and II (%), hemodynamically stable, who compromise at least 36 exercise sessions of a randomly assigned intervention (HIIT, CRT or control group). Endothelial function, cardiopulmonary exercise testing, muscle strength and physical performance were completed at baseline and post-intervention. RESULTS: Although no effects on endothelial function; both HIIT and CRT modalities were able to produce a positive effect on [Formula: see text] peak (HIIT = +2.1±6.5, CRT = +3.0±4.2 and control group = -0.1± 5.3 mL/kg/min, time*group p-value<0,05) and METs (HIIT = +0.6±1.8, CRT = +0.9±1.2 and control group = 0±1.6, time*group p-value<0,05). Only HIIT increased isokinetic torque peak (HIIT = +8.8±55.8, CRT = 0.0±60.7 and control group = 1.6±57.6 Nm) matched p-value<0,05. Regarding the physical performance, the CRT modality reduced chair stand test completion time (HIIT = -0.7±3.1, CRT = -3.3±3.2 and control group = -0.3±2.5 s, matched p-value<0,05 and HIIT improved global physical performance(time*group p<0,05). CONCLUSION: This preliminary study trends to indicate for the first time that high-intensity interval training promotes a jointly superior effect compared to progressive high intensity circuit-resistance training by improving cardiorespiratory fitness, muscular strength, and physical performance. Further research with larger cohort is necessary. CLINICAL TRIAL REGISTRATION NUMBER: ReBEC RBR-668c8v.