Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial.
Study Goal
The researchers aimed to assess whether a bioavailable form of curcumin (HydroCurc) could mitigate the pro-oxidant and inflammatory effects of ferrous sulphate in iron deficiency.
Results Summary
The abstract does not provide specific results regarding curcumin's effects, only stating the study's aim to evaluate its influence on ferrous sulphate-induced inflammation.
Population
Not specified in the abstract.
Effective Dosage
Not provided in the abstract.
Duration
Not specified in the abstract.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Ferrous sulphate (FS) | neutral | iron deficiency (ID) | - | - | is a cost effective, readily available iron supplement | #1 |
oral ferrous iron | increase | inflammation | - | - | is known to induce inflammation | #2 |
oral ferrous iron | increase | gastric side-effects | - | - | causing gastric side-effects | #3 |
Curcumin | neutral | antioxidant effect | - | - | is a potent antioxidant | #4 |
Curcumin | neutral | iron chelation | in-vitro | - | has also been shown to exhibit iron chelation | #5 |
Ferrous sulphate (FS) is a cost effective, readily available iron supplement for iron deficiency (ID). The pro-oxidant effect of oral ferrous iron is known to induce inflammation, causing gastric side-effects and resulting in poor compliance. Curcumin is a potent antioxidant and has also been shown to exhibit iron chelation in-vitro, although it is not established whether these effects are retained in-vivo. The aim of this study was therefore to assess the influence of a formulated bioavailable form of curcumin (HydroCurc