The female mouse is resistant to mild vitamin B
European journal of nutrition
February 1, 2022
Inge van der Stelt et al. (8 authors)
Journal ArticleAnimal Study
Extracted Claims (6)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
diet without vitamin B | no change | liver nicotinamide mononucleotide (NMN) levels | Female C57BL/6RccHsd mice | - | no differences were found | #1 |
diet without vitamin B | no change | body composition | Female C57BL/6RccHsd mice | - | no differences were found | #2 |
diet without vitamin B | no change | whole body energy and substrate metabolism measured by indirect calorimetry | Female C57BL/6RccHsd mice | - | no differences were found | #3 |
diet without vitamin B | no change | liver triacylglycerol metabolism | Female C57BL/6RccHsd mice | - | no differences were found | #4 |
mild vitamin B deficiency | neutral | Expression of seven genes | - | - | respond to | #5 |
diet without vitamin B | no change | vitamin B deficient | female 0NR mice | - | were not | #6 |
Abstract
PURPOSE: Vitamin B METHODS: Female C57BL/6RccHsd mice were subjected for 18 weeks to a diet without vitamin B RESULTS: In the female mice, no differences between the two dietary groups were found in liver nicotinamide mononucleotide (NMN) levels, body composition, whole body energy and substrate metabolism measured by indirect calorimetry, or liver triacylglycerol metabolism. Expression of seven genes that previously were shown to respond to mild vitamin B CONCLUSION: We concluded that the female 0NR mice were not vitamin B
Medical Subject Headings (MeSH)
Adipose Tissue, WhiteAnimalsFemaleLiverMaleMiceMice, Inbred C57BLNADNiacinamideSex FactorsVitamin B DeficiencyVitamins
Study Links
PubMed ID34338868
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