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Yoga therapy to reduce fatigue in cancer: effects of reminder e-mails and long-term efficacy.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
December 1, 2021
Teresa Zetzl et al. (5 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether reminder e-mails could enhance yoga therapy adherence and improve fatigue, depression, and quality of life in cancer patients, while also examining long-term effects of yoga.

Results Summary

Reminder e-mails significantly improved yoga practice frequency and reduced general and emotional fatigue, with practice frequency partially mediating emotional fatigue reduction. Long-term yoga therapy benefits were observed for fatigue, depression, and quality of life, though physical and cognitive fatigue improvements were not linked to practice frequency.

Population

Cancer patients who completed an 8-week yoga therapy program.

Effective Dosage

Weekly reminder e-mails for 24 weeks post-therapy.

Duration

8-week yoga therapy followed by 24-week reminder phase.

Interactions

None mentioned

Extracted Claims (9)
InterventionDirectionEndpointPopulationDosageImpactClaim #
weekly reminder e-mails after yoga therapy
decrease
general fatigue
cancer patients
p=0.038, d=0.42
significantly stronger reduction
#1
weekly reminder e-mails after yoga therapy
decrease
emotional fatigue
cancer patients
p=0.004, d=0.59
significantly stronger reduction
#2
weekly reminder e-mails after yoga therapy
increase
practice frequency
cancer patients
p=0.015, d=0.52
higher increase
#3
practice frequency
decrease
emotional fatigue
cancer patients
indirect effect B=-0.10
partially explained the changes
#4
yoga therapy
decrease
fatigue
cancer patients
F>7.46, p<0.001, d>0.54
long-term effects
#5
yoga therapy
decrease
depression
cancer patients
F>7.46, p<0.001, d>0.54
long-term effects
#6
yoga therapy
increase
quality of life
cancer patients
F>7.46, p<0.001, d>0.54
long-term effects
#7
higher practice frequency
no change
physical fatigue
cancer patients
-
did not lead to higher improvement
#8
higher practice frequency
no change
cognitive fatigue
cancer patients
-
did not lead to higher improvement
#9
Abstract

OBJECTIVE: To examine the efficacy of reminder e-mails to continue yoga therapy on practice frequency and fatigue in cancer patients and long-term effects of yoga on fatigue, depression, and quality of life. METHODOLOGY: One hundred two cancer patients who completed an 8-week yoga therapy were randomly allocated to two groups: reminder (N = 51) vs. no-reminder group (N = 51). After completing yoga therapy, the reminder group received weekly e-mails for 24 weeks, which reminded them of practicing yoga, whereas the no-reminder group did not. Primary outcomes were fatigue and practice frequency, and long-term outcomes were fatigue, depression, and quality of life. Data were assessed using questionnaires after yoga therapy (T1) and 6 months after completing yoga therapy (T2). RESULT: A significantly stronger reduction of general (p = 0.038, d = 0.42) and emotional fatigue (p = 0.004, d = 0.59) and a higher increase of practice frequency (p = 0.015, d = 0.52) between T1 and T2 were found for the reminder group compared to the no-reminder group. In the mediation model, practice frequency as a mediator partially explained the changes in emotional fatigue (indirect effect B =  - 0.10). Long-term effects of yoga therapy regarding fatigue, depression, and quality of life were found (F > 7.46, p < 0.001, d > 0.54). CONCLUSION: Weekly reminder e-mails after yoga therapy can positively affect general and emotional fatigue and help cancer patients with fatigue establish a regular yoga practice at home. However, higher practice frequency did not lead to higher physical or cognitive fatigue improvement, suggesting other factors that mediate efficacy on physical or cognitive fatigue, such as mindfulness or side effects of therapy.

Medical Subject Headings (MeSH)
AnxietyDepressionElectronic MailHumansNeoplasmsQuality of LifeYoga
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations2
Citations/Year0.5
Relative Citation Ratio0.29
NIH Percentile15.2%
Research Impact Scores
APT Score0.25
Weight Score2.21
Normalized Score0.70
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