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Bioavailability of magnesium food supplements: A systematic review.

Nutrition (Burbank, Los Angeles County, Calif.)
September 1, 2021
Marta R Pardo et al. (4 authors)
Journal ArticleReviewSystematic ReviewHuman Study
Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
inorganic magnesium formulations
decrease
bioavailability
-
-
appear to be less bioavailable
#1
organic magnesium formulations
increase
bioavailability
-
-
appear to be more bioavailable
#2
magnesium dietary supplements
no change
physiological magnesium levels
healthy people without prior deficit
-
can maintain physiological levels
#3
magnesium dietary supplements
no change
physiological magnesium levels
older people or those with illnesses or previous subphysiological levels
-
this cannot be assured
#4
Abstract

OBJECTIVES: The market for food supplements is booming thanks to their increased consumption. European regulations include different ways in which vitamins and minerals are administered, without making it clear to the consumer whether one formulation has advantages over the other. The aim of this review was to compare the bioavailability of different forms of magnesium and analyze the differences between them. METHODS: Based on a PICO (population, intervention, comparison, outcome) research question, a search strategy was established for magnesium bioavailability studies comparing different forms in the PubMed, Cochrane, Web of Science, and Scopus databases. We found 433 studies, out of which 14 were finally selected. RESULTS: Inorganic formulations appear to be less bioavailable than organic ones, and the percentage of absorption is dose dependent. CONCLUSIONS: All magnesium dietary supplements can maintain physiological levels in healthy people without prior deficit, although this cannot be assured in older people or those with illnesses or previous subphysiological levels.

Medical Subject Headings (MeSH)
AgedBiological AvailabilityDietary SupplementsHumansMagnesiumMineralsVitamins
Study Links
Citation Metrics
Total Citations20
Citations/Year5.0
Relative Citation Ratio2.46
NIH Percentile80.3%
Research Impact Scores
APT Score0.75
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