Melatonin and neuroblastoma: a novel therapeutic approach.
Study Goal
The researchers aimed to summarize current evidence on melatonin's anti-neuroblastoma effects by examining its impact on cellular pathways.
Results Summary
The study highlights melatonin's potential as an anticancer agent against neuroblastoma, with several investigations indicating its effectiveness through various cellular pathways. However, specific clinical outcomes or statistical significance are not detailed in the abstract.
Population
Children with neuroblastoma (implied by context, not explicitly stated).
Effective Dosage
Not available
Duration
Not available
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
melatonin | decrease | cancer | - | - | having anticancer potentials | #1 |
melatonin | decrease | neuroblastoma | - | - | effects against | #2 |
melatonin | decrease | neuroblastoma | - | - | anti-neuroblastoma effects | #3 |
Neuroblastoma is a deadly and serious malignancy among children. Although many developments have been occurred for the treatment of this disease, the rate of mortality is still high. Therefore, it is necessary to search for novel complementary and alternative therapies. Melatonin, a hormone secreted from pineal gland, is a multifunctional agent having anticancer potentials. Recently, several investigations have been conducted indicating melatonin effects against neuroblastoma. In this paper, we summarize current evidence on anti-neuroblastoma effects of melatonin based on cellular pathways.