The Positive Impact of Resistance Training on Muscle Mass and Serum Leptin Levels in Patients 2-7 Years Post-Roux-en-Y Gastric Bypass: A Controlled Clinical Trial.
Study Goal
The researchers aimed to investigate the effect of a resistance training program (RTP) on body composition and serum inflammatory profile in individuals 2-7 years post-Roux-en-Y gastric bypass (RYGB).
Results Summary
The RTP improved body composition by modestly increasing muscle mass and decreasing serum leptin and CRP levels, particularly in individuals with higher visceral fat area (VFA). The program also contributed to a reduction in proinflammatory markers in long-term RYGB patients.
Population
Individuals 2-7 years post-RYGB, matched by BMI, age, sex, and years after surgery.
Effective Dosage
Not specified
Duration
12 weeks
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Resistance training program (RTP) | no change | body composition | individuals in late Roux-en-Y gastric bypass (RYGB) | - | assist the maintenance of optimal | #1 |
Resistance training program (RTP) | no change | inflammatory response modulation | individuals in late Roux-en-Y gastric bypass (RYGB) | - | assist the maintenance of optimal | #2 |
Resistance training program (RTP) | increase | body composition | individuals 2-7 years post-RYGB | modest but significant | improved | #3 |
Resistance training program (RTP) | increase | muscle mass | individuals 2-7 years post-RYGB | modest but significant | enhancing | #4 |
Resistance training program (RTP) | decrease | serum leptin levels | individuals 2-7 years post-RYGB | - | decreasing | #5 |
Resistance training program (RTP) | decrease | CRPus levels | individuals 2-7 years post-RYGB | - | decreasing | #6 |
Resistance training program (RTP) | no change | body composition | long-term RYGB | - | assist in maintaining the adequate | #7 |
Resistance training program (RTP) | decrease | proinflammatory markers | long-term RYGB | - | contribute to a decrease in | #8 |
PURPOSE: Resistance training program (RTP) assist the maintenance of optimal body composition and inflammatory response modulation in individuals in late Roux-en-Y gastric bypass (RYGB). This study aimed to investigate the effect of RTP on body composition and serum inflammatory profile in individuals 2-7 years post-RYGB. METHODS: Volunteers were matched on body mass index (BMI), age, sex, and years after surgery, and they were allocated as control or RTP group. Body composition, visceral fat area (VFA), and inflammatory serum markers were measured at baseline and after 12 weeks of RTP. RESULTS: The sample baseline characteristics (n = 63; BMI = 29.7 ± 5.3 kg/m CONCLUSION: The RTP improved individuals' body composition by a modest but significant enhancing muscle mass and decreasing serum leptin and CRPus levels, especially in individuals with VFA values above the median. RTPs assist in maintaining the adequate body composition as they contribute to a decrease in proinflammatory markers in long-term RYGB.