No additive effect of acetaminophen when co-ingested with caffeine on cycling performance in well-trained young men.
Journal of applied physiology (Bethesda, Md. : 1985)
January 1, 1970
Søren Jessen et al. (5 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Extracted Claims (6)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
caffeine | increase | power output during a 6-min performance test | Fourteen men [age (means ± SD): 26 ± 6 yr] | - | increased | #1 |
acetaminophen | increase | power output during a 6-min performance test | Fourteen men [age (means ± SD): 26 ± 6 yr] | - | increased | #2 |
caffeine | decrease | peripheral fatigue | Fourteen men [age (means ± SD): 26 ± 6 yr] | - | reduced | #3 |
acetaminophen | decrease | peripheral fatigue | Fourteen men [age (means ± SD): 26 ± 6 yr] | - | reduced | #4 |
caffeine | increase | muscle protein kinase A (PKA) substrate phosphorylation | Fourteen men [age (means ± SD): 26 ± 6 yr] | - | increased | #5 |
acetaminophen | increase | muscle protein kinase A (PKA) substrate phosphorylation | Fourteen men [age (means ± SD): 26 ± 6 yr] | - | increased | #6 |
Abstract
We investigated the effect of caffeine and acetaminophen on power output during a 6-min performance test, peripheral fatigue, and muscle protein kinase A (PKA) substrate phosphorylation. Fourteen men [age (means ± SD): 26 ± 6 yr; V̇o
Medical Subject Headings (MeSH)
AcetaminophenCaffeineDouble-Blind MethodGlycogenHumansMaleMuscle, SkeletalPerformance-Enhancing SubstancesPhosphocreatine
Study Links
PubMed ID34013747
Citation Metrics
Total Citations7
Citations/Year1.8
Relative Citation Ratio0.78
NIH Percentile41.3%
Research Impact Scores
APT Score0.50
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