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Melatonin supplementation improves psychomotor and physical performance in collegiate student-athletes following a sleep deprivation night.

Chronobiology international
May 1, 2021
Nesa Paryab et al. (8 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether melatonin supplementation could mitigate the negative effects of sleep deprivation on psychomotor performance and physical fitness measures in collegiate student-athletes.

Results Summary

Melatonin improved static and dynamic balance, anaerobic power, blood lactate levels, and reaction time compared to placebo under both 4-hour and 24-hour sleep deprivation conditions. The placebo group showed negative effects from sleep deprivation, with more severe impacts after 24 hours.

Population

Ten trained male collegiate student-athletes (mean age 20 ± 2 years).

Effective Dosage

6 mg administered orally 30 minutes before testing.

Duration

Single-dose intervention per session, with six sessions spaced 72 hours apart.

Interactions

None mentioned

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
sleep deprivation
decrease
post-cognitive and physical performance, and other functions
-
-
negatively impacts
#1
melatonin
increase
tolerance to training and competition
-
-
enhances tolerance to training and improves competition
#2
4 h sleep deprivation
decrease
static and dynamic balance, reaction time, and anaerobic power
trained male collegiate student-athletes
-
had negative effect
#3
24 h sleep deprivation
decrease
static and dynamic balance, reaction time, and anaerobic power
trained male collegiate student-athletes
-
had negative effect
#4
melatonin supplementation
increase
static and dynamic balance
trained male collegiate student-athletes
-
had a positive effect
#5
melatonin supplementation
increase
anaerobic power
trained male collegiate student-athletes
-
had a positive effect
#6
melatonin supplementation
decrease
blood lactic acid
trained male collegiate student-athletes
-
had a positive effect
#7
melatonin supplementation
decrease
reaction time
trained male collegiate student-athletes
-
had a positive effect
#8
Abstract

Several studies report sleep deprivation negatively impacts post-cognitive and physical performance, and other functions. Recent findings indicate ingestion of melatonin prior to exercise enhances tolerance to training and improves competition. We investigated the effects of melatonin supplementation on psychomotor performance and selected physical fitness measures of collegiate student-athletes following 4 h and 24 h of sleep deprivation. The study employed a repeated-measures, double-blind, randomized controlled protocol with posttest control group design with six conditions [3 sleep conditions (without sleep deprivation, 4 h sleep deprivation (4SD) and 24 h sleep deprivation (24SD)) × 2 supplementation conditions (melatonin and placebo)]. Ten trained male collegiate student-athletes (mean ± SD; age: 20 ± 2 y) attended the laboratory on six occasions with 72 h between successive visits. Placebo or 6 mg of melatonin were administered orally in capsules 30 min before the tests of: static and dynamic balance, reaction time, and anaerobic power. Also, blood lactate was measured before and 3 min after the anaerobic power exercise. During the placebo session, the results indicated that 4SD and 24SD had negative effect on the measured parameters, with higher impacts of the 24SD condition. Compared to placebo and during both 4SD and 24SD conditions, melatonin had a positive effect on static and dynamic balance, anaerobic power, blood lactic acid, and reaction time (

Medical Subject Headings (MeSH)
AdolescentAdultAthletesCircadian RhythmDietary SupplementsDouble-Blind MethodHumansMaleMelatoninPhysical Functional PerformancePsychomotor PerformanceSleepSleep DeprivationStudentsYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality78/10
Citation Metrics
Total Citations27
Citations/Year6.8
Relative Citation Ratio3.35
NIH Percentile87.2%
Research Impact Scores
APT Score0.75
Weight Score2.61
Normalized Score0.70
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