Effects of mindfulness-and acceptance-based interventions on quality of life, coping, cognition, and mindfulness of people with multiple sclerosis: a systematic review and meta-analysis.
Study Goal
The researchers aimed to examine the effects of mindfulness- and acceptance-based interventions (MABIs) on quality of life, coping, cognition, and mindfulness in people with multiple sclerosis (MS).
Results Summary
The meta-analysis found moderate effects of MABIs on quality of life, coping, and attention, and a large effect on memory at posttest, with a large effect on quality of life at follow-up. No significant effect was found on mindfulness, and the overall risk of bias across studies was unclear.
Population
People with multiple sclerosis (MS)
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
mindfulness- and acceptance-based interventions (MABIs) | increase | quality of life (QoL) | people with multiple sclerosis (MS) | moderate | moderate effects | #1 |
mindfulness- and acceptance-based interventions (MABIs) | increase | coping | people with multiple sclerosis (MS) | moderate | moderate effects | #2 |
mindfulness- and acceptance-based interventions (MABIs) | increase | attention | people with multiple sclerosis (MS) | moderate | moderate effects | #3 |
mindfulness- and acceptance-based interventions (MABIs) | increase | memory | people with multiple sclerosis (MS) | large | large effect | #4 |
mindfulness- and acceptance-based interventions (MABIs) | increase | quality of life (QoL) | people with multiple sclerosis (MS) | large | large effect | #5 |
mindfulness- and acceptance-based interventions (MABIs) | no change | mindfulness | people with multiple sclerosis (MS) | no significant change | no significant effect | #6 |
This systematic review and meta-analysis of randomized controlled trials (RCTs) examined effects of mindfulness- and acceptance-based interventions (MABIs) on quality of life (QoL), coping, cognition, and mindfulness among people with multiple sclerosis (MS). Four electronic databases were searched to 3 July 2020. Data was combined in a random-effects meta-analysis model. Eighteen RCTs met the eligibility criteria. Meta-analyses at the immediate posttest found: moderate effects of MABIs on QoL, coping, and attention; and a large effect on memory. A large effect of MABIs on QoL was found at follow-up. There was no significant effect of MABIs on mindfulness. Relatively fewer studies in outcomes other than QoL were found, and the overall risk of bias across the included 18 RCTs was unclear. Future high-quality studies with follow-up evaluations are needed to support effects of MABIs on QoL, coping, cognition, and mindfulness in people with MS and examine intervention features that increase and maintain effects.