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The Impact of Weight Loss Program in Metabolic Profile and Body Fat Improvement among Indonesian Young Obese: A Randomized Clinical Trial.

Journal of nutritional science and vitaminology
January 1, 2020
Etika Ratna Noer et al. (8 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to investigate the effects of an 8-week high-protein diet combined with exercise on TG/HDL ratio, WHtR, body fat, and body weight in individuals with BMI >25 kg/m².

Results Summary

The study found that an 8-week high-protein diet and exercise intervention improved markers of insulin resistance (TG/HDL ratio) and central adiposity (WHtR), along with reductions in body fat and body weight.

Population

43 subjects with BMI >25 kg/m².

Effective Dosage

Not specified.

Duration

8 weeks.

Interactions

None mentioned.

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
8-wk-high protein diet and exercise
neutral
TG/HDL ratio
43 subjects with BMI >25 kg/m²
-
investigate the effect
#1
8-wk-high protein diet and exercise
neutral
waist to height ratio (WHtR)
43 subjects with BMI >25 kg/m²
-
investigate the effect
#2
8-wk-high protein diet and exercise
neutral
body fat (BF)
43 subjects with BMI >25 kg/m²
-
investigate the effect
#3
8-wk-high protein diet and exercise
neutral
body weight (BW)
43 subjects with BMI >25 kg/m²
-
investigate the effect
#4
Abstract

Abdominal obesity is defined as an accumulation visceral fat in abdomen region. It is linked to metabolic disorders that contribute to chronic diseases. Triglyceride (TG) to high-density lipoprotein (TG/HDL) ratio is considered as an insulin resistance (IR) marker. The waist to height ratio (WHtR) has been advocated as an effective and convenient measurement of central adiposity that could potentially be superior instead of BMI in determining cardiometabolic risk. The objective of this study was to investigate the effect of 8-wk-high protein diet and exercise on TG/HDL ratio, waist to height ratio (WHtR), body fat (BF) and body weight (BW). This study was a randomized clinical trial in 43 subjects with BMI >25 kg/m

Medical Subject Headings (MeSH)
Adipose TissueBody Mass IndexDiet, ReducingHumansIndonesiaMetabolomeObesityRisk FactorsTriglyceridesWaist CircumferenceWeight Reduction Programs
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality75/10
Citation Metrics
Total Citations1
Citations/Year0.2
Relative Citation Ratio0.09
NIH Percentile4.3%
Research Impact Scores
APT Score0.25
Weight Score1.92
Normalized Score0.63
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