Complementary and alternative treatments for insomnia/insomnia -depression-anxiety symptom cluster: Meta-analysis of English and Chinese literature.
Study Goal
The researchers aimed to evaluate the effect of mindfulness-based treatment on insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms compared to non-specific/placebo controls.
Results Summary
Mindfulness-based treatment showed significant between-group differences on sleep measures compared to non-specific/placebo controls, with moderate to large effect sizes, though heterogeneity was high.
Population
Individuals with significant insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
complementary and alternative medicines (CAM) | decrease | sleep symptoms | patients with significant insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms | moderate to large effect sizes | yielded significant, moderate to large effect sizes | #1 |
complementary and alternative medicines (CAM) | decrease | depression symptoms | patients with significant insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms | moderate to large effect sizes | yielded significant, moderate to large effect sizes | #2 |
complementary and alternative medicines (CAM) | decrease | anxiety symptoms | patients with significant insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms | moderate to large effect sizes | yielded significant, moderate to large effect sizes | #3 |
mindfulness-based treatment | decrease | sleep measures | patients with significant insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms | - | significant between-group differences | #4 |
This study systematically reviewed randomized controlled trials (RCT), published in English or Chinese, investigating the effect of complementary and alternative medicines (CAM) on significant insomnia/poor sleep quality and accompanying depression and/or anxiety symptoms. A meta-analysis was completed by calculating within-group effect size (ES) of each CAM treatment on sleep, depression and/or anxiety measures. Moderating analyses of study quality, language, treatment duration and presence of physical diseases were conducted to evaluate their impact on ESs. Between-group ES of CAM (vs. non-specific/placebo controls) were computed among high-quality studies. From an initial pool of 5047 articles, a total of 72 studies were included in the meta-analysis (44 in English; 28 in Chinese). All CAM modalities yielded significant, moderate to large effect sizes on sleep, depression, and anxiety symptoms yet with high heterogeneity. Significant between-group differences on sleep measures were found only between mindfulness-based treatment and non-specific/placebo controls. Chinese literature are associated with larger ESs. Future study should examine the presence and nature of the active components in different CAM approaches.