Panacea Index Logo

Command Palette

Search for a command to run...

Vitamin D: Vitamin or Hormone?

The Nursing clinics of North America
March 1, 2021
Deborah L Ellison et al. (2 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to explore the role of sunlight in vitamin D synthesis and its broader physiological effects.

Results Summary

The study found that sunlight exposure leads to vitamin D synthesis, which functions as a multifunctional hormone influencing immune, cardiovascular, endocrine, and metabolic systems, with potential roles in depression, pain, and cancer.

Population

Not specified

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (7)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Calcitriol
increase
the immune system
-
-
has been shown to have enhancing effects
#1
Calcitriol
increase
the cardiovascular system
-
-
has been shown to have enhancing effects
#2
Calcitriol
increase
the endocrine system
-
-
has been shown to have enhancing effects
#3
Calcitriol
increase
other metabolic pathways
-
-
has been shown to have enhancing effects
#4
vitamin D
neutral
depression
-
-
has also a role in
#5
vitamin D
neutral
pain
-
-
has also a role in
#6
vitamin D
neutral
cancer
-
-
has also a role in
#7
Abstract

Vitamin D can be obtained from diet, direct sunlight, or supplementation. The most common form is synthesized in the skin after exposure to ultraviolet B radiation. Nevertheless, the thought is that vitamin D is more of a multifunctional hormone or prohormone. This is because vitamin D plays contributes to many processes in the body. Calcitriol has been shown to have enhancing effects on the immune system, the cardiovascular system, the endocrine system, and other metabolic pathways. There is evidence that vitamin D has also a role in depression, pain, and cancer.

Medical Subject Headings (MeSH)
AntioxidantsCalcitriolCholecalciferolDietary SupplementsHumansNeoplasmsProtective AgentsReceptors, CalcitriolSunlightVitamin D Deficiency
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations14
Citations/Year3.5
Relative Citation Ratio1.40
NIH Percentile62.5%
Research Impact Scores
APT Score0.50
Weight Score2.43
Normalized Score0.69
Related Supplements