A 6-month, double-blind, placebo-controlled, randomized trial to evaluate the effect of Eurycoma longifolia (Tongkat Ali) and concurrent training on erectile function and testosterone levels in androgen deficiency of aging males (ADAM).
Study Goal
The researchers aimed to determine the effect of Eurycoma longifolia (Tongkat Ali) combined with concurrent training on erectile function and testosterone levels in men with androgen deficiency of aging males (ADAM).
Results Summary
The study found that Tongkat Ali supplementation (200 mg) combined with concurrent training significantly improved erectile function and increased total testosterone levels in men with ADAM, with the most significant results observed in the combined intervention group.
Population
Men aged 47.38 ± 5.03 years with ADAM.
Effective Dosage
200 mg of Eurycoma longifolia.
Duration
6 months.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Eurycoma longifolia | increase | erectile function | men with ADAM | - | improved | #1 |
concurrent training | increase | erectile function | men with ADAM | - | improved | #2 |
concurrent training + Eurycoma longifolia | increase | erectile function | men with ADAM | - | most significant improvements | #3 |
200 mg supplement of Eurycoma longifolia and the practice of concurrent training for 6 months | increase | erectile function | men with ADAM | - | significantly improved | #4 |
combination of Eurycoma longifolia and concurrent training | increase | erectile function | men with ADAM | - | improved | #5 |
combination of Eurycoma longifolia and concurrent training | increase | total testosterone levels | men with ADAM | - | increased | #6 |
BACKGROUND: Androgen deficiency of aging males (ADAM) largely manifests as sexual symptoms. Erectile dysfunction is one of the most common symptoms of ADAM. AIM: To ascertain the effect of concurrent training and supplementation with Eurycoma longifolia on erectile function and testosterone levels in men with ADAM, and the association of erectile function with levels of total testosterone. METHODS: 6-month, randomized, double-blind, placebo-controlled four-arm clinical. 45 men (47.38 ± 5.03 years) were randomized into 4 groups (G1: control + placebo; G2: control + Eurycoma longifolia; G3: concurrent training + placebo; G4: concurrent training + Eurycoma longifolia). 22 received a 200 mg supplement of Eurycoma longifolia and 23 underwent the intervention with concurrent training, 3 times a week for 60 min at progressive intensity. OUTCOMES: International Index of Erectile Function (IIEF-5), Aging Male Scale (AMS) and total testosterone. RESULTS: Erectile function demonstrated improvements in both interventions; however, the most significant results were obtained by men allocated to concurrent training + Eurycoma longifolia. CLINICAL IMPLICATIONS: A 200 mg supplement of Eurycoma longifolia and the practice of concurrent training for 6 months significantly improved the erectile function of men with ADAM. STRENGTHS & LIMITATIONS: The study's design stands out as a strength, in addition to the six-month intervention. The main limitation is the study not having groups that used only Eurycoma longifolia and only concurrent training. CONCLUSION: The combination of Eurycoma longifolia and concurrent training improved erectile function and increased total testosterone levels in men with ADAM.