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Effects of Probiotic (Bacillus subtilis) Supplementation During Offseason Resistance Training in Female Division I Athletes.

Journal of strength and conditioning research
November 1, 2020
Jeremy C Toohey et al. (12 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine the effects of probiotic (Bacillus subtilis) supplementation on physical performance and body composition during offseason resistance training in female Division I athletes.

Results Summary

Probiotic supplementation did not improve physical performance but led to greater reductions in body fat percentage compared to placebo. No other significant group differences were observed in strength or performance metrics.

Population

Female Division I soccer and volleyball players (n=23, aged 19.6 ± 1.0 years).

Effective Dosage

5 billion CFU/day of Bacillus subtilis (DE111).

Duration

10 weeks.

Interactions

None mentioned.

Extracted Claims (10)
InterventionDirectionEndpointPopulationDosageImpactClaim #
probiotic (Bacillus subtilis) supplementation
no change
physical performance
female Division I soccer and volleyball players
no significant change
had no effect
#1
probiotic (Bacillus subtilis) supplementation
increase
body composition
female Division I soccer and volleyball players
-
may improve
#2
probiotic (Bacillus subtilis) supplementation
decrease
body fat %
female Division I athletes
-2.05 ± 1.38%
greater reductions were observed
#3
placebo supplementation
decrease
body fat %
female Division I athletes
-0.2 ± 1.6%
reductions were observed
#4
10-week resistance training program
increase
squat 1RM
female Division I athletes
-
improved
#5
10-week resistance training program
increase
deadlift 1RM
female Division I athletes
-
improved
#6
10-week resistance training program
increase
bench press 1RM
female Division I athletes
-
improved
#7
10-week resistance training program
increase
vertical jump
female Division I athletes
-
improved
#8
10-week resistance training program
increase
rectus femoris muscle thickness
female Division I athletes
-
improved
#9
10-week resistance training program
decrease
body fat %
female Division I athletes
-
improved
#10
Abstract

Toohey, JC, Townsend, JR, Johnson, SB, Toy, AM, Vantrease, WC, Bender, D, Crimi, CC, Stowers, KL, Ruiz, MD, VanDusseldorp, TA, Feito, Y, and Mangine, GT. Effects of probiotic (Bacillus subtilis) supplementation during offseason resistance training in female Division I athletes. J Strength Cond Res 34(11): 3173-3181, 2020-We examined the effects of probiotic (Bacillus subtilis) supplementation during offseason training in collegiate athletes. Twenty-three Division I female athletes (19.6 ± 1.0 years, 67.5 ± 7.4 kg, and 170.6 ± 6.8 cm) participated in this study and were randomized into either a probiotic (n = 11; DE111) or placebo (n = 12; PL) group while counterbalancing groups for sport. Athletes completed a 10-week resistance training program during the offseason, which consisted of 3-4 workouts per week of upper- and lower-body exercises and sport-specific training. Athletes consumed DE111 (DE111; 5 billion CFU/day) or PL supplement daily for the entire 10-week program. Before and after training, all athletes underwent 1 repetition maximum (1RM) strength testing (squat, deadlift, and bench press), performance testing (vertical jump and pro-agility), and isometric midthigh pull testing. Body composition (body fat [BF]%) was completed using BODPOD and bioelectrical impedance analysis, as well as muscle thickness (MT) measurement of the rectus femoris (RF) and vastus lateralis using ultrasonography. Separate repeated-measures analyses of variance were used to analyze all data. Significant (p ≤ 0.05) main effects for time were observed for improved squat 1RM, deadlift 1RM, bench press 1RM, vertical jump, RF MT, and BF%. Of these, a significant group × time interaction was noted for BF% (p = 0.015), where greater reductions were observed in DE111 (-2.05 ± 1.38%) compared with PL (-0.2 ± 1.6%). No other group differences were observed. These data suggest that probiotic consumption in conjunction with post-workout nutrition had no effect on physical performance but may improve body composition in female Division I soccer and volleyball players after offseason training.

Medical Subject Headings (MeSH)
AthletesBacillus subtilisBody CompositionDietary SupplementsFemaleHumansMuscle StrengthMuscle, SkeletalProbioticsResistance TrainingSoccerUltrasonographyVolleyballYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality80/10
Citation Metrics
Total Citations43
Citations/Year8.6
Relative Citation Ratio3.73
NIH Percentile89.1%
Research Impact Scores
APT Score0.75
Weight Score2.57
Normalized Score0.62
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