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Acute effects of aerobic exercise and relaxation training on fatigue in breast cancer survivors: A feasibility trial.

Psycho-oncology
February 1, 2021
Jason Cohen et al. (5 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to test the acceptability and acute effects of combining aerobic exercise with technology-guided mindfulness training on cancer-related fatigue in breast cancer survivors.

Results Summary

The study found preliminary evidence supporting the feasibility and efficacy of combining aerobic exercise with mindfulness training for reducing fatigue in breast cancer survivors, with the combined approach being well-received.

Population

Breast cancer survivors recruited from Central Illinois.

Effective Dosage

Three 90-minute sessions over 7 days.

Duration

7 days.

Interactions

None mentioned.

Extracted Claims (15)
InterventionDirectionEndpointPopulationDosageImpactClaim #
combined aerobic exercise with guided-mindfulness relaxation
decrease
cancer-related fatigue
breast cancer survivors
-
significantly reduced
#1
aerobic exercise only
decrease
cancer-related fatigue
breast cancer survivors
-
significantly reduced
#2
relaxation only
decrease
cancer-related fatigue
breast cancer survivors
-
significantly reduced
#3
combined aerobic exercise with guided-mindfulness relaxation
decrease
perceived stress
breast cancer survivors
-
significantly reduced
#4
aerobic exercise only
decrease
perceived stress
breast cancer survivors
-
significantly reduced
#5
relaxation only
decrease
perceived stress
breast cancer survivors
-
significantly reduced
#6
combined aerobic exercise with guided-mindfulness relaxation
increase
self-efficacy
breast cancer survivors
-
significantly increased
#7
aerobic exercise only
increase
self-efficacy
breast cancer survivors
-
significantly increased
#8
relaxation only
increase
self-efficacy
breast cancer survivors
-
significantly increased
#9
combined aerobic exercise with guided-mindfulness relaxation
increase
mindfulness
breast cancer survivors
-
significantly increased
#10
aerobic exercise only
increase
mindfulness
breast cancer survivors
-
significantly increased
#11
relaxation only
increase
mindfulness
breast cancer survivors
-
significantly increased
#12
combined aerobic exercise with guided-mindfulness relaxation
increase
quality of life
breast cancer survivors
-
significantly increased
#13
aerobic exercise only
increase
quality of life
breast cancer survivors
-
significantly increased
#14
relaxation only
increase
quality of life
breast cancer survivors
-
significantly increased
#15
Abstract

OBJECTIVE: This three-armed randomized controlled feasibility trial tested the acceptability and acute effects of aerobic exercise and technology-guided mindfulness training (relative to standalone interventions) on cancer-related fatigue among breast cancer survivors (BCS). METHODS: BCS recruited from Central Illinois completed pre- and post-testing using established measures and were randomized to one of three groups (combined aerobic exercise with guided-mindfulness relaxation, aerobic exercise only, and relaxation only), conducted in three 90 min sessions over the course of 7 days in a fitness room and research office on a university campus. RESULTS: We enrolled 40 BCS (M CONCLUSIONS: These findings provide preliminary evidence for the feasibility of combining evidence-based techniques to address fatigue among BCS. The combined approach, incorporating mobile health technology, presents an efficacious and well-received design. If replicated in longer trials, the approach could provide a promising opportunity to deliver broad-reaching interventions for improved outcomes in BCS. Preregistered-ClinicalTrials NCT03702712.

Medical Subject Headings (MeSH)
AgedBreast NeoplasmsCancer SurvivorsExerciseFatigueFeasibility StudiesFemaleHumansMiddle AgedMindfulnessRelaxation TherapyTreatment Outcome
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations11
Citations/Year2.8
Relative Citation Ratio0.87
NIH Percentile45.2%
Research Impact Scores
APT Score0.75
Weight Score2.49
Normalized Score0.66
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