Probiotics, Prebiotics and Other Dietary Supplements for Gut Microbiota Modulation in Celiac Disease Patients.
Study Goal
The researchers aimed to evaluate the challenges and limitations of a gluten-free diet (GFD) for celiac disease patients, including adherence issues, nutritional imbalances, and gut microbiota restoration.
Results Summary
The study highlights that GFD, while the only treatment for celiac disease, poses concerns like food cross-contamination, nutritional deficiencies, and incomplete gut microbiota recovery. It suggests potential benefits of supplementing GFD with probiotics.
Population
Celiac disease patients
Effective Dosage
Not available
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
gluten-free diet | neutral | celiac disease | celiac disease patients | - | is the only available treatment | #1 |
gluten-free diet | increase | adverse health consequences | celiac disease patients | significant | lack of adherence leads to a significant risk | #2 |
gluten-free diet | neutral | food cross-contamination, nutritional imbalances, and persistent gastrointestinal symptoms | - | - | are the main concerns related to | #3 |
gluten-free diet | no change | gut microbiota | patients | - | patients struggle in achieving a full restoring of | #4 |
probiotics | neutral | - | - | - | pivotal studies on the supplementation of GFD with | #5 |
To date, the only available treatment for celiac disease (CD) patients is a life-lasting gluten-free diet (GFD). Lack of adherence to the GFD leads to a significant risk of adverse health consequences. Food cross-contamination, nutritional imbalances, and persistent gastrointestinal symptoms are the main concerns related to GFD. Moreover, despite rigid compliance to GFD, patients struggle in achieving a full restoring of the gut microbiota, which plays a role in the nutritive compounds processing, and absorption. Pivotal studies on the supplementation of GFD with probiotics, such as