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Effectiveness of Protein Supplementation Combined with Resistance Training on Muscle Strength and Physical Performance in Elderly: A Systematic Review and Meta-Analysis.

Nutrients
January 1, 1970
Noé Labata-Lezaun et al. (8 authors)
Journal ArticleMeta-AnalysisSystematic ReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the effectiveness of resistance training (RT) combined with protein supplementation (PS) compared to RT alone or with a placebo in improving muscle strength and physical performance in elderly individuals.

Results Summary

The meta-analysis found no statistical differences in upper-limb strength between RT combined with PS and RT alone or with a placebo. Secondary outcomes related to physical performance (SPPB, gait speed, 5CRT) were not fully detailed in the abstract.

Population

Healthy elderly individuals (>60 years)

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (2)
InterventionDirectionEndpointPopulationDosageImpactClaim #
resistance training (RT) and protein supplementation (PS)
increase
muscle strength and physical performance
healthy elderly (>60 years)
-
improvement
#1
resistance training (RT) and protein supplementation (PS)
no change
upper-limb strength
healthy elderly (>60 years)
SMD: 0.56, 95% CI: -0.09, 1.21
no statistical differences
#2
Abstract

The aim of this study was to evaluate the effectiveness of the combination of resistance training (RT) and protein supplementation (PS), compared to RT alone or combined with a placebo (plS), in the improvement of muscle strength and physical performance. The search strategy in PubMed, Cochrane Library, and Web of Sciences databases found a total of 294 studies. Once inclusion and exclusion criteria were applied, 16 studies were included for the qualitative analysis. A total of 657 healthy elderly (>60 years) participants were analysed. Finally, 15 articles were included in the quantitative analysis with one being excluded due to issues with data availability. Upper-limb, lower-limb, and handgrip strength were the primary outcomes of the meta-analysis. The secondary outcomes, related to physical performance, were Short Physical Performance Battery (SPPB), gait speed, and the five-chair-rise test (5CRT). The main results of the meta-analysis show no statistical differences for upper-limb (SMD: 0.56, 95% CI: -0.09, 1.21,

Medical Subject Headings (MeSH)
AgedDietary ProteinsDietary SupplementsGeriatric AssessmentHumansMuscle StrengthPhysical Functional PerformanceResistance Training
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality80/10
Citation Metrics
Total Citations22
Citations/Year4.4
Relative Citation Ratio1.88
NIH Percentile72.7%
Research Impact Scores
APT Score0.75
Weight Score1.75
Normalized Score0.62
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