Panacea Index Logo

Command Palette

Search for a command to run...

Low carbohydrate ketogenic therapy as a metabolic treatment for binge eating and ultraprocessed food addiction.

Current opinion in endocrinology, diabetes, and obesity
October 1, 2020
Shebani Sethi et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to explore the potential of a low-carbohydrate ketogenic diet as a treatment for binge eating and ultraprocessed food addiction by examining its proposed mechanisms.

Results Summary

The study suggests that ultraprocessed, refined, or high-glycemic-index carbohydrates may trigger neurochemical responses similar to addiction, leading to overeating and hunger exacerbation. Reducing or abstaining from these foods could be an effective treatment approach, supported by recent case series.

Population

Not specified (general focus on individuals with binge eating or ultraprocessed food addiction).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
a low carbohydrate ketogenic dietary approach
decrease
symptoms
-
-
may be helpful in alleviating
#1
a diet low in refined carbohydrates, processed sugar and higher fat content
decrease
symptoms
-
-
may be helpful in alleviating
#2
Ultraprocessed, refined or high glycemic index carbohydrates
increase
neurochemical responses similar to addiction
-
-
are a possible trigger mediating
#3
Ultraprocessed, refined or high glycemic index carbohydrates
increase
abnormal blood sugar and insulin spikes
-
-
triggering
#4
Ultraprocessed, refined or high glycemic index carbohydrates
increase
changes in metabolic and neurobiological signaling
-
-
leading to
#5
Ultraprocessed, refined or high glycemic index carbohydrates
increase
overeating symptoms and hunger exacerbation
-
-
results in
#6
healthy fat consumption
no change
insulin spikes
-
-
lack of similar
#7
significantly reducing or abstaining from these addictive-like ultraprocessed foods and highly refined carbohydrates
neutral
a treatment approach
-
-
could be considered
#8
Abstract

PURPOSE OF REVIEW: The aim of this study was to highlight the recent advancements and future directions for potential use of a low carbohydrate ketogenic dietary approach to treat binge eating and ultraprocessed food addiction. Herein, we explore proposed mechanisms of why a diet low in refined carbohydrates, processed sugar and higher fat content may be helpful in alleviating symptoms. RECENT FINDINGS: Emerging evidence suggests there may be a metabolic role in development of maladaptive eating. These findings broaden our understanding of eating psychopathology causes. Ultraprocessed, refined or high glycemic index carbohydrates are a possible trigger mediating neurochemical responses similar to addiction. The carbohydrate-insulin model of obesity supports observations of these foods triggering abnormal blood sugar and insulin spikes subsequently leading to changes in metabolic and neurobiological signaling. This results in overeating symptoms and hunger exacerbation, which differs from observed effects of healthy fat consumption and lack of similar insulin spikes. As supported in recent case series, significantly reducing or abstaining from these addictive-like ultraprocessed foods and highly refined carbohydrates could be considered a treatment approach. SUMMARY: The current review highlights recent and pertinent evidence with respect to theoretical and practical application of low carbohydrate ketogenic therapeutic approaches for ultraprocessed food addiction and binge eating symptoms. VIDEO ABSTRACT:.

Medical Subject Headings (MeSH)
Binge-Eating DisorderDiet, Carbohydrate-RestrictedDiet, KetogenicDietary CarbohydratesFood AddictionFood HandlingFood PreferencesHumansInsulinObesity
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality65/10
Citation Metrics
Total Citations12
Citations/Year2.4
Relative Citation Ratio1.05
NIH Percentile51.9%
Research Impact Scores
APT Score0.50
Weight Score2.07
Normalized Score0.63
Related Supplements