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Melatonin membrane receptors MT

Tropical animal health and production
September 1, 2020
Melissa Carvajal-Serna et al. (8 authors)
Journal ArticleAnimal StudyMolecular Study
Extracted Claims (20)
InterventionDirectionEndpointPopulationDosageImpactClaim #
melatonin
neutral
melatonin biological functions
mammals
-
mediated
#1
melatonin
neutral
membrane receptors MT1 and MT2
-
-
interaction
#2
melatonin
increase
bone mineral density
ovariectomized rats
-
increased
#3
melatonin
increase
bone strength
ovariectomized rats
-
increased
#4
melatonin
increase
serum osteocalcin levels
ovariectomized rats
-
increased
#5
melatonin
decrease
serum C-terminal telopeptide of type I collagen levels
ovariectomized rats
-
decreased
#6
melatonin
increase
bone formation
ovariectomized rats
-
increased
#7
melatonin
decrease
bone resorption
ovariectomized rats
-
decreased
#8
melatonin
increase
expression of osteogenic genes
bone marrow mesenchymal stem cells
-
increased
#9
melatonin
increase
osteogenic differentiation
bone marrow mesenchymal stem cells
-
increased
#10
melatonin
increase
mineralization
bone marrow mesenchymal stem cells
-
increased
#11
melatonin
increase
expression of MT2 receptor
bone marrow mesenchymal stem cells
-
increased
#12
melatonin
increase
expression of osteogenic genes
bone marrow mesenchymal stem cells
-
increased
#13
melatonin
increase
osteogenic differentiation
bone marrow mesenchymal stem cells
-
increased
#14
melatonin
increase
mineralization
bone marrow mesenchymal stem cells
-
increased
#15
melatonin
increase
expression of MT2 receptor
bone marrow mesenchymal stem cells
-
increased
#16
melatonin
increase
expression of osteogenic genes
bone marrow mesenchymal stem cells
-
increased
#17
melatonin
increase
osteogenic differentiation
bone marrow mesenchymal stem cells
-
increased
#18
melatonin
increase
mineralization
bone marrow mesenchymal stem cells
-
increased
#19
melatonin
increase
expression of MT2 receptor
bone marrow mesenchymal stem cells
-
increased
#20
Abstract

In mammals, many melatonin biological functions are mediated through its interaction with the membrane receptors MT

Medical Subject Headings (MeSH)
AnimalsGene Expression RegulationMaleMelatoninPhotoperiodReceptor, Melatonin, MT1Receptor, Melatonin, MT2SeasonsSheepSpermatozoa
Study Links
PubMed ID32445158
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