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Stress-reducing effects of a brief mindfulness intervention in palliative care: Results from a randomised, crossover study.

European journal of cancer care
July 1, 2020
Marco Warth et al. (6 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the stress-reducing effects of a brief, standardized mindfulness intervention for use in palliative care, particularly in patients with advanced cancer or terminal illnesses.

Results Summary

The study found significantly stronger reductions in self-rated stress and mean heart rate, along with increased heart rate variability after the mindfulness intervention. Psychophysiological effects were strongest immediately post-intervention, while subjective stress reduction persisted for 20-40 minutes, though no significant differences were found for self-rated well-being.

Population

Patients with advanced cancer or other terminal illnesses in palliative care.

Effective Dosage

Single mindfulness intervention (specific duration not detailed in abstract).

Duration

Immediate effects measured pre- to post-intervention, with follow-up at 20-40 minutes.

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
a brief, standardised mindfulness intervention
decrease
self-rated stress
patients in very advanced stages of a disease
-
significantly stronger reductions
#1
a brief, standardised mindfulness intervention
decrease
mean heart rate
patients in very advanced stages of a disease
-
significantly stronger reductions
#2
a brief, standardised mindfulness intervention
increase
heart rate variability
patients in very advanced stages of a disease
-
an increase
#3
a brief, standardised mindfulness intervention
no change
self-rated well-being
patients in very advanced stages of a disease
no significant change
No significant differences were found
#4
Abstract

OBJECTIVE: Mindfulness-based interventions are a widely used and highly accepted adjunct treatment in oncology. Due to a paucity of research in advanced cancer and other terminal illnesses, we aimed to evaluate the stress-reducing effects of a brief, standardised mindfulness intervention for use in palliative care. METHODS: This study was a randomised, crossover trial where patients participated in both a single mindfulness intervention and a resting state control condition. The order of the conditions was randomised. Study outcomes encompassed self-report data on stress and well-being and measures of heart rate variability. All outcome data were measured at four times per day. RESULTS: Forty-two patients participated in this study. We found significantly stronger reductions in self-rated stress and mean heart rate as well as an increase in heart rate variability after the mindfulness intervention. Psychophysiological effects were strongest in the immediate pre- to post-intervention comparison, while the effect on subjective stress persisted after 20 to 40 min. No significant differences were found for self-rated well-being. CONCLUSIONS: Despite the rather small magnitude of effects, the brief mindfulness intervention showed to be effective and accepted by patients in very advanced stages of a disease and could be offered by trained healthcare professionals in palliative care.

Medical Subject Headings (MeSH)
AgedCross-Over StudiesFemaleHeart RateHumansMaleMiddle AgedMindfulnessNeoplasmsPalliative CareStress, PhysiologicalStress, Psychological
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations9
Citations/Year1.8
Relative Citation Ratio0.69
NIH Percentile37.1%
Research Impact Scores
APT Score0.75
Weight Score2.38
Normalized Score0.67
Related Supplements
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