Iron Sucrose: A Wealth of Experience in Treating Iron Deficiency.
Study Goal
The researchers aimed to evaluate the role of intravenous iron administration in treating iron deficiency and iron-deficiency anemia, particularly in patients unresponsive to oral iron therapy or with specific conditions like end-stage kidney disease, chronic heart failure, and inflammatory bowel disease.
Results Summary
The study found that intravenous iron administration is effective for treating iron deficiency and anemia in patients who cannot take or do not respond to oral iron, and it is recommended as first-line treatment for certain conditions like end-stage kidney disease, chronic heart failure, and inflammatory bowel disease. Iron sucrose (Venofer) is highlighted as one of the first available intravenous iron preparations.
Population
Patients with iron deficiency or iron-deficiency anemia, particularly those unresponsive to oral iron therapy or with end-stage kidney disease, chronic heart failure, or inflammatory bowel disease.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
oral iron supplementation | decrease | iron deficiency and iron-deficiency anemia | many patient populations | - | can be treated effectively | #1 |
intravenous iron administration | decrease | iron deficiency and iron-deficiency anemia | patients who are unable to take or who do not respond to oral iron therapy | - | is recommended | #2 |
intravenous iron administration | decrease | iron deficiency and iron-deficiency anemia | patients with end-stage kidney disease, chronic heart failure, and inflammatory bowel disease | - | has become first-line treatment | #3 |
Iron deficiency and iron-deficiency anemia are associated with increased morbidity and mortality in a wide range of conditions. In many patient populations, this can be treated effectively with oral iron supplementation; but in patients who are unable to take or who do not respond to oral iron therapy, intravenous iron administration is recommended. Furthermore, in certain conditions, such as end-stage kidney disease, chronic heart failure, and inflammatory bowel disease, intravenous iron administration has become first-line treatment. One of the first available intravenous iron preparations is iron sucrose (Venofer