Effect of Astragalus polysaccharide in treatment of diabetes mellitus: a narrative review.
Study Goal
The researchers aimed to review recent experimental studies on the effects of Astragalus polysaccharides in treating diabetes mellitus and its complications.
Results Summary
The study found that Astragalus polysaccharides showed promising effects in treating diabetes mellitus, including improvements in insulin resistance and secretion, as well as potential benefits for diabetic complications like neuropathy, retinopathy, cardiomyopathy, foot ulcers, and infections.
Population
Not specified (review of experimental studies, likely involving animal models and/or human trials).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Astragalus polysaccharides | decrease | diabetes mellitus | - | - | have been studied widely for treating diabetes mellitus with promising effects | #1 |
Astragalus polysaccharides | neutral | insulin resistance | - | - | effects | #2 |
Astragalus polysaccharides | neutral | insulin secretion | - | - | effects | #3 |
Astragalus polysaccharides | neutral | diabetic neuropathy | - | - | effects | #4 |
Astragalus polysaccharides | neutral | diabetic retinopathy | - | - | effects | #5 |
Astragalus polysaccharides | neutral | diabetic cardiomyopathy | - | - | effects | #6 |
Astragalus polysaccharides | neutral | diabetic foot | - | - | effects | #7 |
Astragalus polysaccharides | neutral | infection complicated by diabetes mellitus | - | - | effects | #8 |
Diabetes mellitus is a chronic endocrine/metabolism disease characterized by hyperglycemia arising from defects in insulin action, insulin secretion, or both. Diabetes mellitus is often complicated by visceral lesions, which can lead to serious complications and death. A variety of new agents are in development for the treatment of the disease. Astragalus polysaccharides are monomer components extracted from the Traditional Chinese Medicine, Huangqi (Radix Astragali Mongolici), which have been studied widely for treating diabetes mellitus with promising effects in recent years. This paper reviews recent advances in experimental studies on the effects of Astragalus polysaccharides in treating diabetes mellitus. The effects of Astragalus polysaccharides on the etiology and complication of diabetes mellitus including insulin resistance and secretion, diabetic neuropathy, diabetic retinopathy, diabetic cardiomyopathy, diabetic foot, and infection complicated by diabetes mellitus are discussed.