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A randomized clinical trial of mindfulness-based cognitive therapy for women with irritable bowel syndrome-Effects and mechanisms.

Journal of consulting and clinical psychology
April 1, 2020
Julia F Henrich et al. (5 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to evaluate the effects of mindfulness-based cognitive therapy adapted for IBS (MBCT-IBS) on symptom reduction and quality of life, as well as investigate its therapeutic mechanisms.

Results Summary

The MBCT-IBS group reported significantly greater reductions in IBS symptoms and improvements in quality of life compared to the control group, with potential mechanisms involving reduced maladaptive illness cognitions and changes in self-processing.

Population

67 female patients with irritable bowel syndrome (IBS).

Effective Dosage

Not specified

Duration

6 weeks

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
mindfulness-based cognitive therapy adapted for patients with IBS (MBCT-IBS)
decrease
IBS symptoms
female patients with IBS
-
significantly greater reductions
#1
mindfulness-based cognitive therapy adapted for patients with IBS (MBCT-IBS)
decrease
maladaptive illness cognitions
female patients with IBS
-
significantly greater reductions
#2
mindfulness-based cognitive therapy adapted for patients with IBS (MBCT-IBS)
decrease
self-referent processing of illness and health
female patients with IBS
-
significantly greater reductions
#3
mindfulness-based cognitive therapy adapted for patients with IBS (MBCT-IBS)
increase
nonjudgmental awareness
female patients with IBS
-
significantly greater increases
#4
mindfulness-based cognitive therapy adapted for patients with IBS (MBCT-IBS)
increase
quality of life
female patients with IBS
-
increase
#5
Abstract

OBJECTIVE: Irritable bowel syndrome (IBS) is a chronic disorder of brain-gut interaction. Previous studies suggest that mindfulness could be therapeutic for IBS patients, however no study has evaluated the effects of mindfulness-based cognitive therapy adapted for patients with IBS (MBCT-IBS). A 6-week MBCT-IBS course was designed to reduce symptoms and increase quality of life. This study aimed to evaluate the effects of MBCT-IBS and to investigate its therapeutic mechanisms in a randomized controlled trial. METHOD: Sixty-seven female patients with IBS were randomized to MBCT-IBS (MG; RESULTS: The MG reported significantly greater reductions in IBS symptoms ( CONCLUSIONS: MBCT-IBS has the potential to reduce IBS symptoms and increase quality of life. MBCT-IBS may exert its effect on IBS symptoms via reducing maladaptive illness cognitions and activating changes in self-processing (reducing biases in self-referent processing of illness and health and increasing nonjudgmental awareness). (PsycINFO Database Record (c) 2020 APA, all rights reserved).

Medical Subject Headings (MeSH)
AdultAnxietyCatastrophizationCognitive Behavioral TherapyFemaleHumansIrritable Bowel SyndromeMiddle AgedMindfulnessQuality of LifeSymptom AssessmentTreatment OutcomeYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations30
Citations/Year6.0
Relative Citation Ratio2.12
NIH Percentile76.2%
Research Impact Scores
APT Score0.95
Weight Score2.50
Normalized Score0.70
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