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Effects of Preconditioning Local Vibrations on Subsequent Plantar Skin Blood Flow Response to Walking.

The international journal of lower extremity wounds
June 1, 2021
Xiaotong Zhu et al. (6 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether preconditioning local vibrations reduce reactive hyperemia after walking in healthy individuals.

Results Summary

The study found that peak skin blood flow (SBF) was significantly lower in the vibration protocol compared to the sham control, suggesting that local vibrations may reduce reactive hyperemia after walking.

Population

10 healthy participants without diabetes mellitus (DM).

Effective Dosage

10-minute local vibrations (100 Hz or sham).

Duration

10-minute intervention periods (baseline, vibration/sham, walking, recovery).

Interactions

None mentioned

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
weight-bearing exercise such as walking
increase
foot ulcers
people with diabetes mellitus (DM)
-
may increase risk
#1
applications of local vibrations on plantar tissues as a preconditioning intervention before walking
decrease
plantar tissue ischemia during walking
people with diabetes mellitus (DM)
-
may reduce
#2
preconditioning local vibrations
decrease
reactive hyperemia after walking
healthy participants without DM
-
reduce
#3
local vibrations (100 Hz)
decrease
peak SBF
healthy participants without DM
6.98 ± 0.87 vs 9.26 ± 1.34
was significantly lower than
#4
Abstract

Weight-bearing exercise such as walking may increase risk of foot ulcers in people with diabetes mellitus (DM) because of plantar ischemia due to repetitive, high plantar pressure. Applications of local vibrations on plantar tissues as a preconditioning intervention before walking may reduce plantar tissue ischemia during walking. The objective of this study was to explore whether preconditioning local vibrations reduce reactive hyperemia after walking. A double-blind, repeated-measures, and crossover design was tested in 10 healthy participants without DM. The protocol included 10-minute baseline, 10-minute local vibrations (100 Hz or sham), 10-minute walking, and 10-minute recovery periods. The order of local vibrations was randomly assigned. Skin blood flow (SBF) was measured over the first metatarsal head during baseline and recovery periods. SBF responses were characterized as peak SBF, total SBF, and recovery time of reactive hyperemia. SBF was expressed as a ratio of recovery to baseline SBF to quantify the changes. Peak SBF in the vibration protocol (6.98 ± 0.87) was significantly lower than the sham control (9.26 ± 1.34,

Medical Subject Headings (MeSH)
Diabetes MellitusHumansRegional Blood FlowSkinVibrationWalking
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality85/10
Citation Metrics
Total Citations4
Citations/Year1.0
Relative Citation Ratio0.62
NIH Percentile33.3%
Research Impact Scores
APT Score0.05
Weight Score2.40
Normalized Score0.67
Related Supplements
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