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Developing and validating equations to predict

Disability and rehabilitation
October 1, 2021
Jennifer Labonté et al. (11 authors)
Journal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to develop new prediction equations for maximal oxygen consumption (V̇O₂) using the 6-Minute Walking Test (6MWT) in childhood ALL survivors.

Results Summary

The study established new clinical V̇O₂ prediction equations based on the 6MWT, suggesting its utility in assessing cardiorespiratory fitness in this population. The abstract implies the 6MWT is a viable method for functional capacity evaluation, though full results are not detailed.

Population

Childhood acute lymphoblastic leukemia (ALL) survivors (n=200, with 168 undergoing tests).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
6-Minute Walking Test (6MWT)
no change
functional capacity
-
-
is a safe, standardized and well utilized method to assess
#1
published prediction equations
no change
valid maximal oxygen consumption (V̇O2max)
-
-
cannot accurately predict
#2
cardiopulmonary exercise test
no change
functional capacity and cardiorespiratory fitness
childhood ALL survivors
-
to assess
#3
6-Minute Walking Test (6MWT)
no change
functional capacity and cardiorespiratory fitness
childhood ALL survivors
-
to assess
#4
new establish clinical V̇O2max prediction equation
increase
V̇O2max
childhood ALL survivors
-
predicted
#5
Abstract

INTRODUCTION: The 6-Minute Walking Test (6MWT) is a safe, standardized and well utilized method to assess the functional capacity. Recently, it was reported that the published prediction equations cannot accurately predict a valid maximal oxygen consumption (V̇O METHODS: A total of 200 childhood ALL survivors were enrolled in this study, among which 168 participants underwent a cardiopulmonary exercise test and a 6MWT to assess their functional capacity and their cardiorespiratory fitness. In addition, participants completed a physical activity questionnaire. Participants were randomly divided in two groups to establish the equations ( RESULTS: The new establish clinical V̇O CONCLUSION: This is the first study that predicted V̇O

Medical Subject Headings (MeSH)
Cardiorespiratory FitnessExercise TestHumansOxygen ConsumptionPrecursor Cell Lymphoblastic Leukemia-LymphomaSurvivorsWalk Test
Study Links
Quality Scores
SafetyNot Assessed
Efficacy75/10
Quality80/10
Citation Metrics
Total Citations5
Citations/Year1.3
Relative Citation Ratio0.36
NIH Percentile19.5%
Research Impact Scores
APT Score0.50
Weight Score2.35
Normalized Score0.66
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Developing and validating equations to predict | Panacea Index