Patients' interpersonal problems as moderators of depression outcomes in a randomized controlled trial comparing mindfulness-based cognitive therapy and a group version of the cognitive-behavioral analysis system of psychotherapy in chronic depression.
Study Goal
The researchers aimed to determine whether interpersonal problems moderated depression outcomes between mindfulness-based cognitive therapy (MBCT) and cognitive behavioral analysis system of psychotherapy (CBASP) in chronically depressed patients.
Results Summary
Higher "vindictive/self-centered" scores were associated with better outcomes in MBCT than CBASP, while higher "nonassertive" scores were linked to better outcomes in CBASP than MBCT. The findings suggest MBCT may be preferable for vindictive/self-centered patients, whereas CBASP may be better for nonassertive patients.
Population
Chronically depressed patients (n=68, split between MBCT and CBASP groups).
Effective Dosage
Not specified (group format, 8-week intervention).
Duration
8 weeks.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
mindfulness-based cognitive therapy (MBCT) | decrease | depression outcomes | chronically depressed patients being vindictive/self-centered | - | were associated with a better outcome | #1 |
cognitive behavioral analysis system of psychotherapy (CBASP) | decrease | depression outcomes | chronically depressed patients being nonassertive | - | were associated with a better outcome | #2 |
OBJECTIVES: Interpersonal problems were examined as moderators of depression outcomes between mindfulness-based cognitive therapy (MBCT) and cognitive behavioral analysis system of psychotherapy (CBASP) in patients with chronic depression. METHODS: Patients received treatment-as-usual and, in addition, were randomized to 8-weeks of MBCT (n = 34) or 8-weeks of CBASP (n = 34). MBCT and CBASP were given in a group format. The Hamilton depression rating scale (HAM-D) was the primary and the Beck Depression Inventory (BDI-II) the secondary outcome. The subscales of the Inventory of interpersonal problems (IIP-32) were moderators. Multilevel models were performed. RESULTS: Higher scores on the "vindictive/self-centered" subscale were associated with a better outcome in MBCT than in CBASP (HAM-D: p < .01; BDI-II: p < .01). Higher scores on the "nonassertive" subscale were associated with a better outcome in CBASP than in MBCT (HAM-D: p < .01; BDI-II: p < .01). CONCLUSIONS: If these results can be replicated in larger trials, MBCT should be preferred to CBASP in chronically depressed patients being vindictive/self-centered, whereas CBASP should be preferred to MBCT in chronically depressed patients being nonassertive.