Effects of Preventive Nutrition Interventions among Adolescents on Health and Nutritional Status in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.
Study Goal
The researchers aimed to assess the impact of micronutrient supplementation, including calcium, on health and nutritional status among adolescents in low- and middle-income countries.
Results Summary
The study found uncertain effects of calcium/vitamin D supplementation on body mass index (BMI), with no significant impact observed. The evidence was of low quality, limiting definitive conclusions.
Population
Adolescents aged 10-19 years in low- and middle-income countries.
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
iron supplementation with or without folic acid | no change | anemia | adolescents aged 10-19 years in low- and middle-income countries (LMICs) | relative risk (RR): 1.04, 95% confidence interval (CI) 0.42, 2.57 | uncertain of the effect | #1 |
iron supplementation with or without folic acid | no change | anemia | adolescents aged 10-19 years in low- and middle-income countries (LMICs) | RR: 1.07, 95% CI: 0.46, 2.52 | uncertain of the effect | #2 |
various micronutrient supplementation/fortification | no change | body mass index (BMI) | adolescents aged 10-19 years in low- and middle-income countries (LMICs) | MD: -0.01 kg/m | uncertain of the effect | #3 |
The objective of this review was to assess the impact of preventive nutrition interventions on health and nutritional status of adolescents aged 10-19 years in low- and middle-income countries (LMICs). We searched the databases until 5 February 2019 without any restrictions on publication, date, language, or publication status. A total of 10 studies (15 papers) including 10,802 participants assessing the impact of micronutrient supplementation/fortification were included in this review. We did not find any study assessing the impact of nutrition education and counseling or macronutrient supplementation among adolescents. Among primary outcomes, we are uncertain of the effect of iron supplementation with or without folic acid on anemia (daily supplementation; relative risk (RR): 1.04, 95% confidence interval (CI) 0.42, 2.57; one study; 1160 participants; low-quality evidence; weekly supplementation; RR: 1.07, 95% CI: 0.46, 2.52; one study; 1247 participants; low-quality evidence). We are also uncertain of the effect of various micronutrient supplementation/fortification on body mass index (BMI) (calcium/vitamin D supplementation; (MD: -0.01 kg/m