Panacea Index Logo

Command Palette

Search for a command to run...

New advances in the treatment of paediatric functional abdominal pain disorders.

The lancet. Gastroenterology & hepatology
March 1, 2020
Neha R Santucci et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to explore the potential of mindfulness meditation as a non-pharmacological intervention for pediatric functional abdominal pain disorders (FAPDs).

Results Summary

The abstract mentions that mindfulness meditation is being investigated for pediatric functional pain, suggesting it as a promising psychological advance, but specific results or outcomes are not detailed.

Population

Children with functional abdominal pain disorders (FAPDs).

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (20)
InterventionDirectionEndpointPopulationDosageImpactClaim #
prokinetics
decrease
postprandial distress and nausea
children with functional abdominal pain disorders (FAPDs)
-
to treat
#1
drugs affecting gastric accommodation
decrease
postprandial distress and nausea
children with functional abdominal pain disorders (FAPDs)
-
to treat
#2
anti-inflammatory agents
decrease
irritable bowel syndrome
children with functional abdominal pain disorders (FAPDs)
-
have a therapeutic role
#3
junctional protein regulators
decrease
irritable bowel syndrome
children with functional abdominal pain disorders (FAPDs)
-
have a therapeutic role
#4
analgesics
decrease
irritable bowel syndrome
children with functional abdominal pain disorders (FAPDs)
-
have a therapeutic role
#5
secretagogues
decrease
irritable bowel syndrome
children with functional abdominal pain disorders (FAPDs)
-
have a therapeutic role
#6
serotonin antagonists
decrease
irritable bowel syndrome
children with functional abdominal pain disorders (FAPDs)
-
have a therapeutic role
#7
peripheral electrical nerve field stimulation to the external ear
neutral
-
children with functional abdominal pain disorders (FAPDs)
-
-
#8
gastric electrical stimulation
neutral
-
children with functional abdominal pain disorders (FAPDs)
-
-
#9
low fructose and fibre based diets
neutral
-
children with functional abdominal pain disorders (FAPDs)
-
-
#10
probiotics
neutral
-
children with functional abdominal pain disorders (FAPDs)
-
-
#11
prebiotics
neutral
-
children with functional abdominal pain disorders (FAPDs)
-
-
#12
synbiotics
neutral
-
children with functional abdominal pain disorders (FAPDs)
-
-
#13
exposure-based cognitive behavioural therapy
decrease
paediatric functional pain
children with functional abdominal pain disorders (FAPDs)
-
being investigated
#14
acceptance and commitment therapy
decrease
paediatric functional pain
children with functional abdominal pain disorders (FAPDs)
-
being investigated
#15
mindfulness meditation
decrease
paediatric functional pain
children with functional abdominal pain disorders (FAPDs)
-
being investigated
#16
acupuncture
decrease
FAPDs
children with functional abdominal pain disorders (FAPDs)
-
gaining popularity in the treatment
#17
moxibustion
decrease
FAPDs
children with functional abdominal pain disorders (FAPDs)
-
gaining popularity in the treatment
#18
yoga
decrease
FAPDs
children with functional abdominal pain disorders (FAPDs)
-
gaining popularity in the treatment
#19
spinal manipulation
decrease
FAPDs
children with functional abdominal pain disorders (FAPDs)
-
gaining popularity in the treatment
#20
Abstract

This Review summarises recent pharmacological and upcoming alternative interventions for children with functional abdominal pain disorders (FAPDs). Pharmacological targets include prokinetics and drugs affecting gastric accommodation to treat postprandial distress and nausea. Similarly, anti-inflammatory agents, junctional protein regulators, analgesics, secretagogues, and serotonin antagonists have a therapeutic role for irritable bowel syndrome. Non-pharmacological treatments include peripheral electrical nerve field stimulation to the external ear, gastric electrical stimulation, dietary interventions such as low fructose and fibre based diets, and nutraceuticals, which include probiotics, prebiotics, and synbiotics. Newer psychological advances such as exposure-based cognitive behavioural therapy, acceptance and commitment therapy, and mindfulness meditation are being investigated for paediatric functional pain. Lastly, alternative therapies such as acupuncture, moxibustion, yoga, and spinal manipulation are also gaining popularity in the treatment of FAPDs.

Medical Subject Headings (MeSH)
Abdominal PainAcceptance and Commitment TherapyAcupunctureAdolescentAnalgesicsAnti-Inflammatory AgentsChildChild, PreschoolCognitive Behavioral TherapyDiet TherapyDietary SupplementsElectric StimulationFemaleHumansIrritable Bowel SyndromeMaleManipulation, SpinalMindfulnessMoxibustionNauseaPostprandial PeriodPrebioticsProbioticsPsychological DistressSecretagoguesSerotonin AntagonistsSynbioticsTreatment OutcomeYogaYoung Adult
Study Links
Quality Scores
SafetyNot Assessed
Efficacy70/10
Quality75/10
Citation Metrics
Total Citations24
Citations/Year4.8
Relative Citation Ratio2.29
NIH Percentile78.5%
Research Impact Scores
APT Score0.75
Weight Score2.37
Normalized Score0.63
Related Supplements