New advances in the treatment of paediatric functional abdominal pain disorders.
Study Goal
The researchers aimed to explore the potential of mindfulness meditation as a non-pharmacological intervention for pediatric functional abdominal pain disorders (FAPDs).
Results Summary
The abstract mentions that mindfulness meditation is being investigated for pediatric functional pain, suggesting it as a promising psychological advance, but specific results or outcomes are not detailed.
Population
Children with functional abdominal pain disorders (FAPDs).
Effective Dosage
Not specified
Duration
Not specified
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
prokinetics | decrease | postprandial distress and nausea | children with functional abdominal pain disorders (FAPDs) | - | to treat | #1 |
drugs affecting gastric accommodation | decrease | postprandial distress and nausea | children with functional abdominal pain disorders (FAPDs) | - | to treat | #2 |
anti-inflammatory agents | decrease | irritable bowel syndrome | children with functional abdominal pain disorders (FAPDs) | - | have a therapeutic role | #3 |
junctional protein regulators | decrease | irritable bowel syndrome | children with functional abdominal pain disorders (FAPDs) | - | have a therapeutic role | #4 |
analgesics | decrease | irritable bowel syndrome | children with functional abdominal pain disorders (FAPDs) | - | have a therapeutic role | #5 |
secretagogues | decrease | irritable bowel syndrome | children with functional abdominal pain disorders (FAPDs) | - | have a therapeutic role | #6 |
serotonin antagonists | decrease | irritable bowel syndrome | children with functional abdominal pain disorders (FAPDs) | - | have a therapeutic role | #7 |
peripheral electrical nerve field stimulation to the external ear | neutral | - | children with functional abdominal pain disorders (FAPDs) | - | - | #8 |
gastric electrical stimulation | neutral | - | children with functional abdominal pain disorders (FAPDs) | - | - | #9 |
low fructose and fibre based diets | neutral | - | children with functional abdominal pain disorders (FAPDs) | - | - | #10 |
probiotics | neutral | - | children with functional abdominal pain disorders (FAPDs) | - | - | #11 |
prebiotics | neutral | - | children with functional abdominal pain disorders (FAPDs) | - | - | #12 |
synbiotics | neutral | - | children with functional abdominal pain disorders (FAPDs) | - | - | #13 |
exposure-based cognitive behavioural therapy | decrease | paediatric functional pain | children with functional abdominal pain disorders (FAPDs) | - | being investigated | #14 |
acceptance and commitment therapy | decrease | paediatric functional pain | children with functional abdominal pain disorders (FAPDs) | - | being investigated | #15 |
mindfulness meditation | decrease | paediatric functional pain | children with functional abdominal pain disorders (FAPDs) | - | being investigated | #16 |
acupuncture | decrease | FAPDs | children with functional abdominal pain disorders (FAPDs) | - | gaining popularity in the treatment | #17 |
moxibustion | decrease | FAPDs | children with functional abdominal pain disorders (FAPDs) | - | gaining popularity in the treatment | #18 |
yoga | decrease | FAPDs | children with functional abdominal pain disorders (FAPDs) | - | gaining popularity in the treatment | #19 |
spinal manipulation | decrease | FAPDs | children with functional abdominal pain disorders (FAPDs) | - | gaining popularity in the treatment | #20 |
This Review summarises recent pharmacological and upcoming alternative interventions for children with functional abdominal pain disorders (FAPDs). Pharmacological targets include prokinetics and drugs affecting gastric accommodation to treat postprandial distress and nausea. Similarly, anti-inflammatory agents, junctional protein regulators, analgesics, secretagogues, and serotonin antagonists have a therapeutic role for irritable bowel syndrome. Non-pharmacological treatments include peripheral electrical nerve field stimulation to the external ear, gastric electrical stimulation, dietary interventions such as low fructose and fibre based diets, and nutraceuticals, which include probiotics, prebiotics, and synbiotics. Newer psychological advances such as exposure-based cognitive behavioural therapy, acceptance and commitment therapy, and mindfulness meditation are being investigated for paediatric functional pain. Lastly, alternative therapies such as acupuncture, moxibustion, yoga, and spinal manipulation are also gaining popularity in the treatment of FAPDs.