The role of iron repletion in adult iron deficiency anemia and other diseases.
Study Goal
The researchers aimed to review the etiologies of iron deficiency anemia (IDA), including bariatric surgery, and discuss treatment options such as IV iron.
Results Summary
The abstract mentions bariatric surgery as one of the causes of IDA but does not provide specific findings about its effects. It highlights the shift toward IV iron for treating IDA due to its effectiveness and improved safety profile.
Population
Not specified (general discussion of IDA etiologies, including bariatric surgery patients).
Effective Dosage
Not mentioned
Duration
Not mentioned
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
intravenous (IV) iron | increase | treatment landscape for many causes of IDA | patients with IDA | - | shifting toward more abundant use | #1 |
intravenous (IV) iron | increase | treatment of IDA | patients with IDA | - | effectiveness | #2 |
improved formulations of IV iron | decrease | adverse effects | - | - | decrease the likelihood | #3 |
IV iron | increase | heart failure | patients with heart failure | - | efficacy | #4 |
IV iron | increase | restless leg syndrome | patients with restless leg syndrome | - | efficacy | #5 |
IV iron | increase | fatigue | patients with fatigue | - | efficacy | #6 |
IV iron | increase | prevention of acute mountain sickness | - | - | efficacy | #7 |
iron supplementation | increase | other conditions | - | - | benefit | #8 |
Iron deficiency anemia (IDA) is the most prevalent and treatable form of anemia worldwide. The clinical management of patients with IDA requires a comprehensive understanding of the many etiologies that can lead to iron deficiency including pregnancy, blood loss, renal disease, heavy menstrual bleeding, inflammatory bowel disease, bariatric surgery, or extremely rare genetic disorders. The treatment landscape for many causes of IDA is currently shifting toward more abundant use of intravenous (IV) iron due to its effectiveness and improved formulations that decrease the likelihood of adverse effects. IV iron has found applications beyond treatment of IDA, and there is accruing data about its efficacy in patients with heart failure, restless leg syndrome, fatigue, and prevention of acute mountain sickness. This review provides a framework to diagnose, manage, and treat patients presenting with IDA and discusses other conditions that benefit from iron supplementation.