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Effects of Leucine-Enriched Whey Protein Supplementation on Physical Function in Post-Hospitalized Older Adults Participating in 12-Weeks of Resistance Training Program: A Randomized Controlled Trial.

Nutrients
January 1, 1970
Maria Amasene et al. (10 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

The researchers aimed to determine whether a whey protein supplement enriched with leucine, combined with resistance training, improved muscle mass and strength in post-hospitalized elderly individuals.

Results Summary

Both the protein supplementation and placebo groups showed improvements in physical function after 12 weeks of resistance training, but the abstract does not specify whether leucine-enriched supplementation provided additional benefits over placebo.

Population

Post-hospitalized elderly individuals.

Effective Dosage

Not specified in the abstract.

Duration

12 weeks.

Interactions

None mentioned.

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
resistance training
decrease
age-related strength and muscle mass loss
-
-
has been proposed as an effective countermeasure
#1
a whey protein supplement enriched with leucine after resistance training
increase
muscle mass and strength gains
a post-hospitalized elderly population
-
the effect of
#2
resistance training
increase
physical function
28 participants
-
improvements in
#3
protein supplementation following resistance training
increase
physical function
28 participants
-
improvements in
#4
placebo supplementation following resistance training
increase
physical function
28 participants
-
improvements in
#5
Abstract

Age-related strength and muscle mass loss is further increased after acute periods of inactivity. To avoid this, resistance training has been proposed as an effective countermeasure, but the additional effect of a protein supplement is not so clear. The aim of this study was to examine the effect of a whey protein supplement enriched with leucine after resistance training on muscle mass and strength gains in a post-hospitalized elderly population. A total of 28 participants were included and allocated to either protein supplementation or placebo supplementation following resistance training for 12 weeks (2 days/week). Physical function (lower and upper body strength, aerobic capacity and the Short Physical Performance Battery (SPPB) test), mini nutritional assessment (MNA) and body composition (Dual X-ray Absorptiometry) were assessed at baseline and after 12 weeks of resistance training. Both groups showed improvements in physical function after the intervention (

Medical Subject Headings (MeSH)
Age FactorsAgedAged, 80 and overDietary SupplementsFemaleHumansLeucineMaleMuscle ContractionMuscle StrengthMuscle, SkeletalNutritional StatusNutritive ValuePatient DischargeProspective StudiesRecovery of FunctionResistance TrainingSarcopeniaSingle-Blind MethodSpainTime FactorsTreatment OutcomeWhey Proteins
Study Links
Quality Scores
SafetyNot Assessed
Efficacy65/10
Quality75/10
Citation Metrics
Total Citations33
Citations/Year5.5
Relative Citation Ratio2.64
NIH Percentile82.1%
Research Impact Scores
APT Score0.95
Weight Score1.74
Normalized Score0.61
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