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Alcohol Consumption Can be a "Double-Edged Sword" for Chronic Kidney Disease Patients.

Medical science monitor : international medical journal of experimental and clinical research
January 1, 1970
Zhenliang Fan et al. (5 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to clarify the relationship between alcohol consumption (particularly wine) and chronic kidney disease (CKD), addressing inconsistencies in existing studies.

Results Summary

The study found that light-to-moderate alcohol consumption may benefit CKD patients but cautioned against non-drinkers starting to drink due to potential adverse events. Conflicting results were noted, possibly due to complex drinking patterns and study design limitations.

Population

Patients with chronic kidney disease (CKD) and general alcohol consumers.

Effective Dosage

Light-to-moderate drinking (specific amounts not detailed).

Duration

Not specified.

Interactions

None mentioned.

Extracted Claims (4)
InterventionDirectionEndpointPopulationDosageImpactClaim #
light-to-moderate alcohol consumption
increase
health
CKD patients
-
beneficial
#1
alcohol consumption
decrease
health
non-drinkers
-
can lead to adverse events
#2
light-to-moderate alcohol consumption
no change
kidney health
patients with CKD
-
may not pose a risk
#3
small amounts of alcohol
increase
death risk
-
-
can be associated with increased death risk
#4
Abstract

Excessive drinking of alcohol is becoming a worldwide problem, and people have recognized that there exists a close relationship between chronic kidney disease (CKD) and alcohol consumption. However, there are many inconsistencies between experimental and clinical studies on alcohol consumption and kidney damage. The possible reason for this contradictory conclusion is the complex drinking pattern of humans and some bioactivators in wine. In addition, the design itself of the clinical studies can also produce conflicting interpretations of the results. Considering the benefits of light-to-moderate alcohol consumption, we recommend that CKD patients continue light-to-moderate drinking, which is beneficial to them. Because alcohol consumption can lead to adverse events, we do not advise non-drinkers to start to drink. Although light-to-moderate alcohol consumption may not pose a risk to patients with CKD, the patients' condition needs to be considered. Consumption of even small amounts of alcohol can be associated with increased death risk. Additional clinical and experimental studies are needed to clarify the effect of alcohol on the kidneys and alcohol consumption on CKD patients.

Medical Subject Headings (MeSH)
Alcohol DrinkingConfounding Factors, EpidemiologicHemodynamicsHumansOxidative StressRenal Insufficiency, ChronicRisk Factors
Study Links
Quality Scores
Safety50
Efficacy60/10
Quality70/10
Citation Metrics
Total Citations28
Citations/Year4.7
Relative Citation Ratio1.67
NIH Percentile68.8%
Research Impact Scores
APT Score0.75
Weight Score1.65
Normalized Score0.58
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