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Effectiveness of the Combined Treatment of Functional Electrical Stimulation and Deambulation in Diabetic Arteriopathy.

Annals of vascular surgery
November 1, 2019
Ma Lourdes Del Río Solá et al. (2 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

To determine whether functional electrical stimulation (FES) during walking improves ischemic pain and quality of life in patients with diabetic arteriopathy (DA) in grade-IIa Leriche-Le Fontaine.

Results Summary

Both diabetic and nondiabetic groups reported improvement after FES-assisted walking, with statistically significant improvements in the diabetic group across all studied parameters except for the 6-minute walk test. Greater benefits were observed in the diabetic group after follow-up.

Population

Patients with grade-IIa Leriche-Le Fontaine peripheral arterial disease in both lower extremities, with and without diabetes mellitus (DM).

Effective Dosage

1 hour of supervised treadmill walking with FES.

Duration

3 months (including follow-up).

Interactions

None mentioned

Extracted Claims (6)
InterventionDirectionEndpointPopulationDosageImpactClaim #
functional electrical stimulation (FES) while walking
decrease
ischemic pain
patients with diabetic arteriopathy (DA) in grade-IIa Leriche-Le Fontaine
-
improved
#1
functional electrical stimulation (FES) while walking
increase
quality of life
patients with diabetic arteriopathy (DA) in grade-IIa Leriche-Le Fontaine
-
improved
#2
functional electrical stimulation (FES) while walking
increase
all the parameters studied
diabetic (DM) group
-
improvement after the treatment
#3
functional electrical stimulation (FES) while walking
increase
all the parameters
diabetic (DM) group after the follow-up
-
greater benefits were observed
#4
functional electrical stimulation (FES) while walking
decrease
intermittent claudication
patients with DA
-
effective
#5
functional electrical stimulation (FES) while walking
increase
quality of life
patients with DA
-
improving
#6
Abstract

OBJECTIVE: To determine whether functional electrical stimulation (FES) is able to improve ischemic pain and quality of life of patients with diabetic arteriopathy (DA) in grade-IIa Leriche-Le Fontaine. MATERIAL AND METHODS: This is a single-blinded, randomized, prospective cohort study. We included patients diagnosed with grade-IIa Leriche-Le Fontaine peripheral arterial disease in both lower extremities with and without diabetes mellitus (DM). The ankle-brachial index was 0.4-0.9. Patients were randomized into two experimental groups: nondiabetic (non-DM) (n = 71) and diabetic (DM) (n = 71). The patients received FES while walking for 1 hr on a supervised treadmill. Three months of follow-up were conducted after treatment. RESULTS: A total of 168 patients were randomized; 142 completed the study, with 71 in each group. Both groups reported an improvement after the treatment, but the improvement was statistically significant in the DM group, in which all the parameters studied improved. Greater benefits were observed in all the parameters in the DM group after the follow-up, except for the test of the meters walked in 6 min. CONCLUSIONS: The use of FES during daily walking is effective in patients with DA, reducing intermittent claudication and improving the quality of life of these patients.

Medical Subject Headings (MeSH)
AgedCombined Modality TherapyDiabetic AngiopathiesDouble-Blind MethodElectric Stimulation TherapyExercise TherapyExercise ToleranceFemaleHumansIntermittent ClaudicationIschemiaMaleMiddle AgedPeripheral Arterial DiseaseProspective StudiesQuality of LifeRecovery of FunctionSpainTime FactorsTreatment OutcomeWalking
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality80/10
Citation Metrics
Total Citations2
Citations/Year0.3
Relative Citation Ratio0.15
NIH Percentile7.5%
Research Impact Scores
APT Score0.05
Weight Score1.93
Normalized Score0.70
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