Is Bacillus coagulans supplementation plus low FODMAP diet superior to low FODMAP diet in irritable bowel syndrome management?
Study Goal
The researchers aimed to determine whether adding Bacillus coagulans to a low FODMAP diet was superior to a low FODMAP diet alone in reducing IBS symptoms.
Results Summary
Both groups showed significant improvements in IBS symptoms, but the probiotic group had greater improvement in symptom severity scores and more patients with clinical improvement on the IBS-SSS scale.
Population
Fifty IBS patients meeting Rome IV criteria.
Effective Dosage
Not specified (abstract mentions "10" but is incomplete).
Duration
8 weeks.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) diet plus Bacillus coagulans supplementation | decrease | reduction of irritable bowel syndrome (IBS) symptoms | IBS patients who met Rome IV criteria for IBS | - | superiority | #1 |
low FODMAP diet plus a probiotic capsule | decrease | abdominal pain intensity | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #2 |
low FODMAP diet plus a probiotic capsule | decrease | abdominal pain frequency | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #3 |
low FODMAP diet plus a probiotic capsule | decrease | abdominal distension | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #4 |
low FODMAP diet plus a probiotic capsule | increase | satisfaction with bowel habits | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #5 |
low FODMAP diet plus a probiotic capsule | increase | quality of life | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #6 |
low FODMAP diet plus a probiotic capsule | improved | defecation consistency | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #7 |
low FODMAP diet plus a probiotic capsule | decrease | patient-reported severity score | IBS patients who met Rome IV criteria for IBS | - | Significant improvements were observed | #8 |
low FODMAP diet plus a probiotic capsule | decrease | severity score | probiotic group | P = 0.001 | improvement was significantly higher | #9 |
low FODMAP diet plus a probiotic capsule | increase | IBS-symptom severity scale (IBS-SSS) | probiotic group | P = 0.038 | frequency of patients with clinical improvement was significantly more | #10 |
probiotic supplement containing B. coagulans added to the low FODMAP diet | decrease | alleviating IBS symptoms | - | - | might be superior | #11 |
PURPOSE: The aim of this study was to assess the superiority of low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) diet plus Bacillus coagulans supplementation to low FODMAP diet alone in the reduction of irritable bowel syndrome (IBS) symptoms. METHODS: In this randomized clinical trial, fifty IBS patients who met Rome IV criteria for IBS were randomly assigned to receive a low FODMAP diet plus either a probiotic or a placebo capsule for 8 weeks. Probiotic capsules contained 10 RESULTS: Significant improvements were observed in abdominal pain intensity and frequency, abdominal distension, satisfaction with bowel habits, quality of life, defecation consistency, and patient-reported severity score in both groups; however, only improvement in severity score was significantly higher in probiotic group compared with placebo group (P = 0.001). Moreover, the frequency of patients with clinical improvement in IBS-symptom severity scale (IBS-SSS) was significantly more in probiotic group compared to placebo group (P = 0.038). CONCLUSION: Our results indicate that the addition of probiotic supplement containing B. coagulans to the low FODMAP diet might be superior to low FODMAP diet in alleviating IBS symptoms.