A randomized controlled trial of mindfulness-based stress reduction for insomnia secondary to cervical cancer: Sleep effects.
Study Goal
To evaluate the efficacy of mindfulness-based stress reduction on sleep parameters and hypnotic medication use in cervical cancer patients with insomnia.
Results Summary
Mindfulness-based stress reduction improved subjective sleep parameters (total wake time, sleep efficacy, total sleep time) post-intervention but showed no significant improvement in objective sleep parameters or long-term effects.
Population
Patients with insomnia caused or worsened by cervical cancer.
Effective Dosage
8-week mindfulness-based stress reduction program (specific frequency not detailed).
Duration
8 weeks.
Interactions
None mentioned.
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
mindfulness-based stress reduction | increase | subjective sleep parameters | patients with insomnia secondary to cervical cancer | Total wake time: ∆ = 45.32, P < 0.05; Sleep efficacy: ∆ = 6.87, P < 0.05; Total sleep time: ∆ = 22.22, P < 0.01 | had a positive effect on | #1 |
mindfulness-based stress reduction | no change | polysomnography data | patients with insomnia secondary to cervical cancer | - | were not improved significantly | #2 |
mindfulness-based stress reduction | increase | patients with insomnia that was secondary to cervical cancer | patients with insomnia secondary to cervical cancer | - | had a definite impact on | #3 |
mindfulness-based stress reduction | no change | patients with insomnia that was secondary to cervical cancer | patients with insomnia secondary to cervical cancer | - | no long-term influences | #4 |
AIM: To evaluate the efficacy of mindfulness-based stress reduction on objective and subjective sleep parameters and hypnotic medication use of patients with insomnia secondary to cervical cancer. METHODS: This was a randomized controlled trial enrolled insomnia patient who were caused or worsened by cervical cancer. Seventy patients with insomnia caused or aggravated by cervical cancer were at random divided into either a usual care group or an 8-week mindfulness-based stress reduction group. Subjective sleep parameters, objective sleep parameters and hypnotic medication consumption were assessed at baseline, after the program, 6- and 12-month after finishing the interventions. RESULTS: The results showed that mindfulness-based stress reduction had a positive effect on subjective sleep parameters (Total wake time: ∆ = 45.32, P < 0.05; Sleep efficacy: ∆ = 6.87, P < 0.05; Total sleep time: ∆ = 22.22, P < 0.01). Compared with control group, polysomnography data in mindfulness-based stress reduction group were not improved significantly. There were no associations between subjective sleep parameters and objective sleep parameters. CONCLUSION: Mindfulness-based stress reduction had a definite impact on patients with insomnia that was secondary to cervical cancer just after the intervention, but no long-term influences. TRIAL REGISTRATION: ChiCTR1800018571; 9/25/2018; retrospectively registered.