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Effect of iron supplementation from neonatal period on the iron status of6-month-old infants at-risk for early iron deficiency: a randomized interventional trial.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
May 1, 2021
Reeta Bora et al. (5 authors)
Journal ArticleRandomized Controlled TrialHuman StudyClinical
Study Details

Study Goal

To investigate the effects of early iron supplementation on hemoglobin levels, serum ferritin, and motor development in infants at risk of early iron deficiency.

Results Summary

Iron-supplemented infants showed higher hemoglobin levels and serum ferritin at 6 months compared to controls, along with improved motor development.

Population

Term infants (37-41 weeks) of anemic mothers (Hb ≤ 100 g/L).

Effective Dosage

Not specified

Duration

From the second day after birth until 6 months

Interactions

None mentioned

Extracted Claims (5)
InterventionDirectionEndpointPopulationDosageImpactClaim #
iron supplementation from the second day after birth
increase
Hb
infants at risk of early iron deficiency
103.7 ± 9.3 g L
had higher
#1
iron supplementation from the second day after birth
increase
serum ferritin
infants at risk of early iron deficiency
55.5 ± 33.4 μg L
had higher
#2
iron supplementation from the second day after birth
increase
motor development
infants at risk of early iron deficiency
94.5 ± 4.1
had higher
#3
iron supplementation from the second day after birth
increase
iron status
infants at risk for early iron deficiency
-
is effective for improving
#4
iron supplementation from the second day after birth
increase
motor development
infants at risk for early iron deficiency
-
is effective for improving
#5
Abstract

OBJECTIVE: To investigate the effects of iron supplementation from the second day after birth on 6-month hemoglobin (Hb), serum ferritin and motor development in infants at risk of early iron deficiency. STUDY DESIGN: Term (37-41 weeks) infants of anemic (Hb ≤ 100 g L RESULTS: Iron-supplemented infants had higher Hb (103.7 ± 9.3 g L CONCLUSION: Early Iron supplementation is effective for improving iron status and motor development at 6 months in infants at risk for early iron deficiency.

Medical Subject Headings (MeSH)
Anemia, Iron-DeficiencyDietary SupplementsFemaleFerritinsHemoglobinsHumansInfantInfant, NewbornIron
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality75/10
Citation Metrics
Total Citations12
Citations/Year3.0
Relative Citation Ratio1.48
NIH Percentile64.7%
Research Impact Scores
APT Score0.75
Weight Score2.41
Normalized Score0.69
Related Supplements
Effect of iron supplementation from neonatal period on the i... | Panacea Index