Therapeutic strategies for type 2 diabetes mellitus in women after menopause.
Study Goal
The researchers aimed to analyze and critically appraise the literature regarding optimal therapeutic strategies for type 2 diabetes mellitus (T2DM) in postmenopausal women.
Results Summary
The abstract highlights lifestyle interventions (dietary changes, physical exercise, weight loss) and metformin as cornerstone treatments for T2DM in postmenopausal women, but does not mention bariatric surgery.
Population
Postmenopausal women with type 2 diabetes mellitus.
Effective Dosage
Not mentioned
Duration
Not mentioned
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Lifestyle interventions, including changes in dietary habits and physical exercise in everyday life | decrease | weight loss | postmenopausal women with type 2 diabetes mellitus | 5% | targeting | #1 |
Limited intake of alcohol and sodium | neutral | endothelial health | postmenopausal women with type 2 diabetes mellitus | - | are additional lifestyle changes for | #2 |
Limited intake of alcohol and sodium | neutral | bone health | postmenopausal women with type 2 diabetes mellitus | - | are additional lifestyle changes for | #3 |
smoking cessation | neutral | endothelial health | postmenopausal women with type 2 diabetes mellitus | - | are additional lifestyle changes for | #4 |
smoking cessation | neutral | bone health | postmenopausal women with type 2 diabetes mellitus | - | are additional lifestyle changes for | #5 |
metformin | neutral | - | postmenopausal women with type 2 diabetes mellitus | - | should be initially treated with | #6 |
As type 2 diabetes mellitus (T2DM) is affected by both chronological and ovarian ageing, it is common in postmenopausal women. This review analyses and critically appraises the literature regarding the optimal therapeutic strategies for T2DM in women after menopause. Lifestyle interventions, including changes in dietary habits and physical exercise in everyday life targeting a modest weight loss (5%), represent the cornerstone of management. Limited intake of alcohol and sodium, as well as smoking cessation, are additional lifestyle changes for both endothelial and bone health. Regarding medications, postmenopausal women should be initially treated with metformin, concurrently with lifestyle intervention. If glycosylated haemoglobin (HbA