There is a growing interest to use mindfulness-based interventions (MBIs) for occupational health promotion. As most evidence for the beneficial effects comes from convenience samples in the social/education/health sector, it is still an open question if MBIs are effective in other contexts, or for whom MBIs are more effective. In addition, self-selection and sample characteristics may have biased previous findings. Theoretically and practically, it is important to know whether MBIs are also effective for nonselective samples outside the social and health sector, especially in agentic and male-oriented cultures. Therefore, this study investigates the effects of a MBI on physiological and psychological criteria in a nonselective sample of police officers. Moreover, this study examines whether effectiveness depends on participants' personality (neuroticism, openness, and conscientiousness) and on perceived social norms toward MBIs. Using a pre-post intervention design,