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The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer's Disease-A Review.

Advances in nutrition (Bethesda, Md.)
January 1, 1970
Annelien C van den Brink et al. (4 authors)
Journal ArticleSystematic ReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the associations of the Mediterranean, DASH, and MIND diets with cognitive decline, dementia, and Alzheimer's disease.

Results Summary

Higher adherence to the Mediterranean diet was associated with better cognitive scores in most studies and a lower risk of Alzheimer's disease, with the strongest associations observed for the MIND diet.

Population

General population, with a focus on cognitive decline and dementia risk.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (15)
InterventionDirectionEndpointPopulationDosageImpactClaim #
higher adherence to the Mediterranean diet
increase
cognitive scores
cross-sectional studies
9 of 12
was associated with better cognitive scores
#1
higher adherence to the Mediterranean diet
increase
cognitive scores
longitudinal studies
17 of 25
was associated with better cognitive scores
#2
higher adherence to the Mediterranean diet
increase
cognitive scores
trials
1 of 3
was associated with better cognitive scores
#3
higher adherence to the DASH diet
increase
cognitive function
cross-sectional study
1
was associated with better cognitive function
#4
higher adherence to the DASH diet
increase
cognitive function
longitudinal studies
2 of 5
was associated with better cognitive function
#5
higher adherence to the DASH diet
increase
cognitive function
trial
1
was associated with better cognitive function
#6
higher adherence to the MIND diet
increase
cognitive scores
cross-sectional study
1
was associated with better cognitive scores
#7
higher adherence to the MIND diet
increase
cognitive scores
longitudinal studies
2 of 3
was associated with better cognitive scores
#8
higher adherence to the Mediterranean diet
decrease
risk of AD
case-control study
1
was associated with a lower risk of AD
#9
higher adherence to the Mediterranean diet
decrease
risk of AD
longitudinal studies
6 of 8
was associated with a lower risk of AD
#10
higher adherence to the DASH diet
decrease
AD risk
longitudinal study
1
was associated with a lower AD risk
#11
higher adherence to the MIND diet
decrease
AD risk
longitudinal study
1
was associated with a lower AD risk
#12
olive oil
decrease
cognitive decline
-
-
may be associated with less cognitive decline
#13
higher adherence to the Mediterranean, DASH, or MIND diets
decrease
cognitive decline
-
-
is associated with less cognitive decline
#14
higher adherence to the Mediterranean, DASH, or MIND diets
decrease
risk of AD
-
-
is associated with a lower risk of AD
#15
Abstract

As there is currently no cure for dementia, there is an urgent need for preventive strategies. The current review provides an overview of the existing evidence examining the associations of the Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets and their dietary components with cognitive decline, dementia, and Alzheimer's disease (AD). A systematic search was conducted within Ovid Medline for studies published up to 27 March 2019 and reference lists from existing reviews and select articles were examined to supplement the electronic search results. In total, 56 articles were included. Higher adherence to the Mediterranean diet was associated with better cognitive scores in 9 of 12 cross-sectional studies, 17 of 25 longitudinal studies, and 1 of 3 trials. Higher adherence to the DASH diet was associated with better cognitive function in 1 cross-sectional study, 2 of 5 longitudinal studies, and 1 trial. Higher adherence to the MIND diet was associated with better cognitive scores in 1 cross-sectional study and 2 of 3 longitudinal studies. Evidence on the association of these dietary patterns with dementia in general was limited. However, higher adherence to the Mediterranean diet was associated with a lower risk of AD in 1 case-control study and 6 of 8 longitudinal studies. Moreover, higher adherence to the DASH or MIND diets was associated with a lower AD risk in 1 longitudinal study. With respect to the components of these dietary patterns, olive oil may be associated with less cognitive decline. In conclusion, current scientific evidence suggests that higher adherence to the Mediterranean, DASH, or MIND diets is associated with less cognitive decline and a lower risk of AD, where the strongest associations are observed for the MIND diet.

Medical Subject Headings (MeSH)
AdultAgedAged, 80 and overAlzheimer DiseaseCase-Control StudiesCognitive DysfunctionCross-Sectional StudiesDiet, MediterraneanDietary Approaches To Stop HypertensionFemaleHumansLongitudinal StudiesMEDLINEMaleMiddle AgedNeurodegenerative Diseases
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality78/10
Citation Metrics
Total Citations317
Citations/Year52.8
Relative Citation Ratio18.32
NIH Percentile99.3%
Research Impact Scores
APT Score0.95
Weight Score2.07
Normalized Score0.70
Related Supplements
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