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A Comparison of Mindfulness-Based Cognitive Therapy Vs Cognitive Behavioral Therapy for the Treatment of Provoked Vestibulodynia in a Hospital Clinic Setting.

The journal of sexual medicine
June 1, 2019
Lori A Brotto et al. (8 authors)
Comparative StudyJournal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tHuman StudyClinical
Study Details

Study Goal

The researchers aimed to compare the effectiveness of mindfulness-based cognitive therapy (MBCT) with cognitive behavioral therapy (CBT) in treating provoked vestibulodynia (PVD), particularly focusing on self-reported pain during vaginal penetration and psychological endpoints.

Results Summary

MBCT showed greater improvements in self-reported pain during vaginal penetration compared to CBT, while both therapies led to similar significant improvements in other endpoints (e.g., pain catastrophizing, sexual function) with benefits maintained at 6 months.

Population

130 women with clinically diagnosed provoked vestibulodynia (PVD), mean ages 31.2 (CBT group) and 33.7 (MBCT group).

Effective Dosage

Not specified

Duration

Immediate post-treatment and 6-month follow-up (exact intervention duration not specified).

Interactions

None mentioned

Extracted Claims (14)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Cognitive behavioral therapy (CBT)
decrease
genital pain intensity
-
-
significantly reduces
#1
Cognitive behavioral therapy (CBT)
increase
psychological and sexual well-being
-
-
improves
#2
mindfulness-based approaches
increase
pain intensity
general chronic pain populations
-
may be as effective for improving
#3
mindfulness-based cognitive therapy (MBCT)
decrease
self-reported pain during vaginal penetration
participants with provoked vestibulodynia (PVD)
-
improvements with MBCT were greater than those with CBT
#4
mindfulness-based cognitive therapy (MBCT)
decrease
pain ratings with a vulvalgesiometer
participants with provoked vestibulodynia (PVD)
-
both groups led to similar significant improvements
#5
mindfulness-based cognitive therapy (MBCT)
decrease
pain catastrophizing
participants with provoked vestibulodynia (PVD)
-
both groups led to similar significant improvements
#6
mindfulness-based cognitive therapy (MBCT)
decrease
pain hypervigilance
participants with provoked vestibulodynia (PVD)
-
both groups led to similar significant improvements
#7
mindfulness-based cognitive therapy (MBCT)
increase
pain acceptance
participants with provoked vestibulodynia (PVD)
-
both groups led to similar significant improvements
#8
mindfulness-based cognitive therapy (MBCT)
increase
sexual function
participants with provoked vestibulodynia (PVD)
-
both groups led to similar significant improvements
#9
mindfulness-based cognitive therapy (MBCT)
decrease
sexual distress
participants with provoked vestibulodynia (PVD)
-
both groups led to similar significant improvements
#10
mindfulness-based cognitive therapy (MBCT)
no change
all other endpoints
participants with provoked vestibulodynia (PVD)
-
benefits were maintained at 6 months
#11
Mindfulness
decrease
self-reported pain from vaginal penetration
-
-
is a promising approach to improving
#12
Mindfulness
no change
several psychological endpoints
-
-
is as effective as CBT for
#13
mindfulness
no change
most pain- and sexuality-related endpoints
participants with provoked vestibulodynia (PVD)
-
is as effective for
#14
Abstract

INTRODUCTION: Chronic and distressing genito-pelvic pain associated with vaginal penetration is most frequently due to provoked vestibulodynia (PVD). Cognitive behavioral therapy (CBT) significantly reduces genital pain intensity and improves psychological and sexual well-being. In general chronic pain populations, mindfulness-based approaches may be as effective for improving pain intensity as CBT. AIM: To compare mindfulness-based cognitive therapy (MBCT) with CBT in the treatment of PVD. METHODS: To ensure power of 0.95 to find medium effect size or larger in this longitudinal design, we enrolled 130 participants. Of these, 63 were assigned to CBT (mean age 31.2 years), and 67 to MBCT (mean age 33.7 years). Data from all participants who completed baseline measures were analyzed, with intent-to-treat analyses controlling for years since diagnosis. MAIN OUTCOME MEASURES: Our primary outcome was self-reported pain during vaginal penetration at immediate post-treatment and at 6 months' follow-up. Secondary endpoints included pain ratings with a vulvalgesiometer, pain catastrophizing, pain hypervigilance, pain acceptance, sexual function, and sexual distress. RESULTS: There was a significant interaction between group and time for self-reported pain, such that improvements with MBCT were greater than those with CBT. For all other endpoints, both groups led to similar significant improvements, and benefits were maintained at 6 months. CLINICAL IMPLICATIONS: Mindfulness is a promising approach to improving self-reported pain from vaginal penetration and is as effective as CBT for several psychological endpoints. STRENGTH & LIMITATIONS: A strength of the present study was the robust sample size (n = 130 women) who had received confirmed clinical diagnoses of PVD. CONCLUSION: The present study showed mindfulness to be as effective for most pain- and sexuality-related endpoints in the treatment of PVD. Brotto LA, Bergeron S, Zdaniuk B, et al. A Comparison of Mindfulness-Based Cognitive Therapy Vs Cognitive Behavioral Therapy for the Treatment of Provoked Vestibulodynia in a Hospital Clinic Setting. J Sex Med 2019;16:909-923.

Medical Subject Headings (MeSH)
AdultAnxietyCatastrophizationChronic PainCognitive Behavioral TherapyFemaleHumansMindfulnessPain MeasurementPelvic PainSample SizeSelf ReportSexual BehaviorVulvodynia
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality90/10
Citation Metrics
Total Citations52
Citations/Year8.7
Relative Citation Ratio5.09
NIH Percentile93.2%
Research Impact Scores
APT Score0.75
Weight Score2.62
Normalized Score0.72
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