Melatonin MT
Pharmacological research
June 1, 2019
Stefano Comai et al. (7 authors)
Journal ArticleResearch Support, Non-U.S. Gov'tReviewHuman StudyMolecular Study
Extracted Claims (12)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Melatonin (MLT) | decrease | anti-inflammatory effects | in vitro cell cultures | - | exerts | #1 |
Melatonin (MLT) | decrease | antioxidant effects | in vitro cell cultures | - | exerts | #2 |
Melatonin (MLT) | decrease | anti-apoptotic effects | in vitro cell cultures | - | exerts | #3 |
Melatonin (MLT) | increase | neuroprotective effects | in vitro cell cultures | - | exerts | #4 |
Melatonin (MLT) | decrease | anti-inflammatory effects | in vivo animal models | - | exerts | #5 |
Melatonin (MLT) | decrease | antioxidant effects | in vivo animal models | - | exerts | #6 |
Melatonin (MLT) | decrease | anti-apoptotic effects | in vivo animal models | - | exerts | #7 |
Melatonin (MLT) | increase | neuroprotective effects | in vivo animal models | - | exerts | #8 |
Melatonin (MLT) | decrease | anti-inflammatory effects | human participants | - | exerts | #9 |
Melatonin (MLT) | decrease | antioxidant effects | human participants | - | exerts | #10 |
Melatonin (MLT) | decrease | anti-apoptotic effects | human participants | - | exerts | #11 |
Melatonin (MLT) | increase | neuroprotective effects | human participants | - | exerts | #12 |
Abstract
Melatonin (MLT), a neuromodulator mainly acting through two G-protein coupled receptors MT
Medical Subject Headings (MeSH)
AnimalsCircadian RhythmDrug DiscoveryHumansLigandsMolecular Targeted TherapyMood DisordersNeurodegenerative DiseasesPsychotic DisordersReceptor, Melatonin, MT1Sleep Wake DisordersSubstance-Related Disorders
Study Links
PubMed ID31029764
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