Effects of full-fat dairy products on subclinical vascular function in adults with elevated blood pressure: a randomized clinical trial.
Study Goal
The researchers aimed to determine whether adding whole milk and full-fat dairy products to the normal diet improves vascular function in adults with elevated blood pressure.
Results Summary
The study found no significant differences in vascular function measures (pulse wave velocity, arterial compliance, baroreceptor sensitivity, or flow-mediated dilation) between high dairy and no dairy conditions, indicating no effect of full-fat dairy on subclinical vascular function.
Population
Adults aged 58 ± 2 years with elevated blood pressure (systolic 120-159 mmHg, diastolic <99 mmHg).
Effective Dosage
Four daily servings of whole milk or full-fat dairy products.
Duration
Two 4-week dietary periods separated by a 2-week washout.
Interactions
None mentioned
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
adding whole milk and full-fat dairy products to the normal routine diet | no change | subclinical vascular function | adults with elevated BP | - | has no effect on | #1 |
high dairy condition consisting of adding four daily servings of whole milk or full-fat dairy products | no change | Carotid-femoral pulse wave velocity (cfPWV) | adults with elevated BP | - | did not differ significantly | #2 |
high dairy condition consisting of adding four daily servings of whole milk or full-fat dairy products | no change | ultrasound-derived vascular distension measures (arterial compliance, beta-stiffness index, and elastic modulus) | adults with elevated BP | - | did not differ significantly | #3 |
high dairy condition consisting of adding four daily servings of whole milk or full-fat dairy products | no change | Cardiovagal baroreceptor sensitivity (via Valsalva maneuver) | adults with elevated BP | - | demonstrated no significant difference | #4 |
high dairy condition consisting of adding four daily servings of whole milk or full-fat dairy products | no change | Brachial arterial flow-mediated dilation (FMD) | adults with elevated BP | - | did not differ significantly | #5 |
BACKGROUND: High consumption of low- and non-fat dairy products improves vascular dysfunction associated with elevated arterial blood pressure (BP). Currently, it is unknown if conventional full-fat dairy products improve vascular functions. OBJECTIVES: To determine if adding whole milk and full-fat dairy products to the normal routine diet improves vascular function in adults with elevated BP. DESIGN: Sixty adults (age ± SEM; 58 ± 2 years) with elevated BP (systolic/diastolic; 120-159/ < 99 mmHg) were randomized into a controlled crossover intervention trial consisting of two 4-week dietary periods. The high dairy condition consisted of adding four daily servings of whole milk or full-fat dairy products to the normal diet and eliminated all dairy intake during the control (no dairy) condition. A 2-week washout period separated the dietary conditions. RESULTS: Carotid-femoral pulse wave velocity (cfPWV) did not differ significantly between high dairy (11.3 ± 0.3 versus 10.9 ± 0.3 m/sec) and no dairy conditions (11.2 ± 0.3 versus 11.0 ± 0.3 m/sec). The results were consistent when ultrasound-derived vascular distension measures (arterial compliance, beta-stiffness index, and elastic modulus) were evaluated. Cardiovagal baroreceptor sensitivity (via Valsalva maneuver) demonstrated no significant difference for either dietary condition. Brachial arterial flow-mediated dilation (FMD) did not differ significantly during the high dairy (5.7 ± 0.5 versus 5.4 ± 0.6%) and no dairy conditions (6.5 ± 0.5 versus 5.6 ± 0.6%). CONCLUSIONS: The solitary addition of whole milk and full-fat dairy products has no effect on subclinical vascular function in adults with elevated BP.