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Macronutrient and Micronutrient Intake during Pregnancy: An Overview of Recent Evidence.

Nutrients
January 1, 1970
Aya Mousa et al. (3 authors)
Journal ArticleReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the effectiveness of calcium supplementation in preventing hypertensive disorders of pregnancy, particularly in high-risk women or those with low dietary calcium intake.

Results Summary

The study found that calcium supplementation is effective in preventing hypertensive disorders of pregnancy, especially in high-risk women or those with low dietary calcium intake. Newly published studies support its use for this purpose.

Population

Pregnant women, particularly those at high risk for hypertensive disorders or with low dietary calcium intake.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (8)
InterventionDirectionEndpointPopulationDosageImpactClaim #
Energy restriction
decrease
gestational weight gain
women with obesity
-
can limit
#1
balanced energy/protein supplementation
increase
birthweight
undernourished women
-
may increase
#2
high protein supplementation
decrease
foetal growth
undernourished women
-
could have adverse effects on
#3
Modulating carbohydrate intake via a reduced glycaemic index or glycaemic load diet
decrease
gestational diabetes
-
-
may prevent
#4
Modulating carbohydrate intake via a reduced glycaemic index or glycaemic load diet
decrease
large-for-gestational-age infants
-
-
may prevent
#5
folic acid
decrease
neural tube defects
-
-
to prevent
#6
iodine
decrease
cretinism
-
-
to prevent
#7
calcium supplementation
decrease
hypertensive disorders of pregnancy
women at high risk or with low dietary calcium intake
-
to prevent
#8
Abstract

Nutritional status during pregnancy can have a significant impact on maternal and neonatal health outcomes. Requirements for macronutrients such as energy and protein increase during pregnancy to maintain maternal homeostasis while supporting foetal growth. Energy restriction can limit gestational weight gain in women with obesity; however, there is insufficient evidence to support energy restriction during pregnancy. In undernourished women, balanced energy/protein supplementation may increase birthweight whereas high protein supplementation could have adverse effects on foetal growth. Modulating carbohydrate intake via a reduced glycaemic index or glycaemic load diet may prevent gestational diabetes and large-for-gestational-age infants. Certain micronutrients are also vital for improving pregnancy outcomes, including folic acid to prevent neural tube defects and iodine to prevent cretinism. Newly published studies support the use of calcium supplementation to prevent hypertensive disorders of pregnancy, particularly in women at high risk or with low dietary calcium intake. Although gaps in knowledge remain, research linking nutrition during pregnancy to maternofoetal outcomes has made dramatic advances over the last few years. In this review, we provide an overview of the most recent evidence pertaining to macronutrient and micronutrient requirements during pregnancy, the risks and consequences of deficiencies and the effects of supplementation on pregnancy outcomes.

Medical Subject Headings (MeSH)
Dietary SupplementsEnergy IntakeFemaleHumansInfant, NewbornMaternal Nutritional Physiological PhenomenaMicronutrientsNutrientsNutritional StatusPregnancyPregnancy ComplicationsPregnancy OutcomePrenatal Care
Study Links
Quality Scores
SafetyNot Assessed
Efficacy85/10
Quality90/10
Citation Metrics
Total Citations244
Citations/Year40.7
Relative Citation Ratio18.73
NIH Percentile99.3%
Research Impact Scores
APT Score0.95
Weight Score2.23
Normalized Score0.72
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