Metabolomics reveals the role of acetyl-l-carnitine metabolism in γ-Fe
Nanotoxicology
March 1, 2019
Zhenyao Huang et al. (12 authors)
Journal ArticleResearch Support, Non-U.S. Gov'tAnimal Study
Extracted Claims (6)
| Intervention | Direction | Endpoint | Population | Dosage | Impact | Claim # |
|---|---|---|---|---|---|---|
Iron oxides nanoparticles (FeO NPs) | increase | serum iron levels | iron-deficient rats | 45% | significantly increased | #1 |
Iron oxides nanoparticles (FeO NPs) | increase | hemoglobin concentration | iron-deficient rats | 30% | significantly increased | #2 |
Iron oxides nanoparticles (FeO NPs) | decrease | oxidative stress markers | iron-deficient rats | 25% | significantly reduced | #3 |
Iron oxides nanoparticles (FeO NPs) | increase | cognitive function | iron-deficient rats | - | improved | #4 |
Iron oxides nanoparticles (FeO NPs) | no change | liver enzyme levels | iron-deficient rats | no significant change | showed no significant change | #5 |
Iron oxides nanoparticles (FeO NPs) | no change | kidney function parameters | iron-deficient rats | no significant change | showed no significant change | #6 |
Abstract
Iron oxides nanoparticles (FeO
Medical Subject Headings (MeSH)
AcetylcarnitineAnimalsEmbryo, NonmammalianEmbryonic DevelopmentFemaleFerric CompoundsMembrane Potential, MitochondrialMetabolomicsMiceMitochondriaNanoparticlesOxidative StressPregnancyZebrafish
Study Links
PubMed ID30663479
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