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Maternal nutritional status and related pregnancy outcomes following bariatric surgery: A systematic review.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
February 1, 2019
Amihai Rottenstreich et al. (6 authors)
Journal ArticleSystematic ReviewHuman Study
Study Details

Study Goal

The researchers aimed to evaluate the association between maternal nutritional status (including calcium) and maternal/perinatal outcomes in postbariatric surgery pregnancies.

Results Summary

The study found calcium deficiencies among pregnant postbariatric surgery patients, but no adverse events specifically linked to calcium deficiency were documented. Evidence of calcium deficiency affecting pregnancy outcomes was lacking.

Population

Women of childbearing age who underwent bariatric surgery and subsequently became pregnant.

Effective Dosage

Not specified

Duration

Not specified

Interactions

None mentioned

Extracted Claims (10)
InterventionDirectionEndpointPopulationDosageImpactClaim #
bariatric surgery
increase
fertility
women with obesity
-
improved
#1
maternal nutritional status
no change
maternal and perinatal outcomes
pregnant postbariatric surgery patients
-
is not well established
#2
-
decrease
maternal concentrations of vitamins A, B1, B6, B12, C, D, K, iron, calcium, selenium, and phosphorous
women with pregnancies after bariatric surgery
-
deficiencies were reported
#3
vitamin B12 deficiency
increase
anemia
pregnant postbariatric surgery patients
-
adverse events documented
#4
iron deficiency
increase
anemia
pregnant postbariatric surgery patients
-
adverse events documented
#5
vitamin A deficiency
increase
night blindness
pregnant postbariatric surgery patients
-
adverse events documented
#6
vitamin A deficiency
increase
urinary tract infections
pregnant postbariatric surgery patients
-
adverse events documented
#7
vitamin D deficiency
increase
urinary tract infections
pregnant postbariatric surgery patients
-
adverse events documented
#8
micronutrient deficiencies
increase
-
pregnant postbariatric surgery patients
-
are common
#9
micronutrient deficiencies
no change
adversely affect pregnancy outcomes (e.g., lower neonatal birth weight)
pregnant postbariatric surgery patients
-
evidence of such is lacking
#10
Abstract

Up to 80% of patients who undergo bariatric surgery are women of childbearing age. Coupled with improved fertility in women with obesity after bariatric surgery, pregnancy postbariatric surgery has become increasingly more common. Although numerous studies have evaluated associations of bariatric surgery with pregnancy outcomes, the effect of maternal nutritional status on maternal and perinatal outcomes is not well established. We used Medline and Embase databases and a manual search of references for articles published until June 2018 to conduct a systematic review on nutritional status after bariatric surgery and its association with maternal and perinatal outcomes. Of the 306 initially identified articles, 27 met the study inclusion criteria, comprising 2056 women with pregnancies after bariatric surgery. Deficiencies were reported in maternal concentrations of vitamins A, B1, B6, B12, C, D, K, iron, calcium, selenium, and phosphorous. The only adverse events documented for these deficiencies encountered during pregnancy were anemia (vitamin B12, iron), night blindness (vitamin A), and urinary tract infections (vitamin A, D). This systematic review suggests that various micronutrient deficiencies are common among pregnant postbariatric surgery patients. Nevertheless, despite the concern that these deficiencies could adversely affect pregnancy outcomes (e.g., lower neonatal birth weight), evidence of such is lacking. Further prospective studies are warranted to confirm our findings and better delineate the optimal supplementation regimen during pregnancy after bariatric surgery.

Medical Subject Headings (MeSH)
Bariatric SurgeryFemaleHumansMaternal HealthNutritional StatusObesity, MorbidPregnancyPregnancy Complications
Study Links
Quality Scores
SafetyNot Assessed
Quality75/10
Citation Metrics
Total Citations50
Citations/Year8.3
Relative Citation Ratio3.87
NIH Percentile89.7%
Research Impact Scores
APT Score0.95
Weight Score2.33
Normalized Score0.55
Related Supplements
Maternal nutritional status and related pregnancy outcomes f... | Panacea Index